| アブストラクト | The intention of prescription medications is to help cure disease or alleviate symptoms; however, sometimes the drugs can cause patient injury, known as an adverse drug event (ADE). With the substantial rise in the use of medications, there has been a concomitant increase in the occurrence of ADEs reported to the FDA. However, the FDA's Adverse Event Reporting System only requires drug manufacturers to report ADEs while many ADEs are often reported in hospitals instead. Between 2004 and 2008, there was a 52 percent increase in the number of ADEs reported in U.S. hospitals. Adverse drug events increase the risk of death, the length of hospitalization, and the cost of care., Hospital stays involving ADEs have been reported for a range of drugs, including hormones, analgesics, antibiotics, and cardiovascular drugs, among others. Adverse drug events may be a reason for admission to the hospital-that is, the ADE was present on admission (POA). Alternatively, ADEs may originate during the hospital stay because of medications administered during hospitalization. Adverse drug events are the most common nonsurgical adverse events in hospitals. In 2008, about 14 percent of Medicare patients experienced an adverse event originating during their hospital stay, costing an estimated $3.8 billion a year, with about a third of the events being ADEs. This Statistical Brief presents more recent data on national ADE rates over all payers in 2011. |
|---|
