| アブストラクト | OBJECTIVE: The objective of the study was to evaluate and summarize reports to the Vaccine Adverse Event Reporting System (VAERS), a spontaneous reporting system, in pregnant women who received influenza A (H1N1) 2009 monovalent vaccine to assess for potential vaccine safety problems. STUDY DESIGN: We reviewed reports of adverse events (AEs) in pregnant women who received 2009-H1N1 vaccines from Oct. 1, 2009, through Feb. 28, 2010. RESULTS: VAERS received 294 reports of AEs in pregnant women who received 2009-H1N1 vaccine: 288 after inactivated and 6 after the live attenuated vaccines. Two maternal deaths were reported. Fifty-nine women (20.1%) were hospitalized. We verified 131 pregnancy-specific outcomes: 95 spontaneous abortions (<20 weeks); 18 stillbirths (>/=20 weeks); 7 preterm deliveries (<37 weeks); 3 threatened abortions; 2 preterm labor; 2 preeclampsia; and 1 each of fetal hydronephrosis, fetal tachycardia, intrauterine growth retardation, and cleft lip. CONCLUSION: Review of reports to VAERS following H1N1 vaccination in pregnant women did not identify any concerning patterns of maternal or fetal outcomes. |
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| ジャーナル名 | American journal of obstetrics and gynecology |
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| 投稿日 | 2011/08/25 |
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| 投稿者 | Moro, Pedro L; Broder, Karen; Zheteyeva, Yenlik; Revzina, Natalya; Tepper, Naomi; Kissin, Dmitry; Barash, Faith; Arana, Jorge; Brantley, Mary D; Ding, Helen; Singleton, James A; Walton, Kimp; Haber, Penina; Lewis, Paige; Yue, Xin; Destefano, Frank; Vellozzi, Claudia |
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| 組織名 | Immunization Safety Office, Division of Healthcare Quality Promotion, National;Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control;and Prevention, Atlanta, GA, USA. pmoro@cdc.gov |
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| Pubmed リンク | https://www.ncbi.nlm.nih.gov/pubmed/21861964/ |
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