| アブストラクト | AIM: To evaluate the clinical outcome of endoscopic submucosal dissection using the Clutch Cutter (ESDCC) in older patients. METHODS: We reviewed 232 consecutive patients with early gastric cancer who underwent ESDCC between June 2010 and February 2014 at Aso Iizuka Hospital. We divided patients into two groups according to age: Older patients (> 80 years, n = 64) and non-older patients (</= 80 years, n = 168). We retrospectively compared the prevalence rates of pre-existing comorbidities, anticoagulant therapy, en bloc resection, mean duration of hospitalization, incidence of ESDCC-related complications, change in performance status (PS) before and after ESDCC, and financial cost of admission. RESULTS: The older group comprised 64 patients with a mean age of 84.1 years, and the non-older group comprised 168 patients with a mean age of 69.5 years. Older patients had significantly more pre-existing comorbidities than did non-older patients, specifically heart disease (P < 0.05). The en bloc resection rate in non-older patients was significantly higher than that in older patients (100% vs 95.3%, P = 0.02). There were no significant differences between the older and non-older groups in the incidence of ESDCC-related complications (i.e., postoperative bleeding and perforation) and the post-ESDCC change in PS. There were also no significant differences between the older and non-older groups in the mean duration of hospitalization (11.4 and 10.7 d, respectively) and financial cost of admission (657040 JPY and 574890 JPY, respectively). CONCLUSION: ESDCC has a good clinical outcome in older patients. |
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| ジャーナル名 | World journal of gastrointestinal oncology |
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| 投稿日 | 2017/11/1 |
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| 投稿者 | Otsuka, Yoshihiro; Akahoshi, Kazuya; Yasunaga, Kayoko; Kubokawa, Masaru; Gibo, Junya; Osada, Shigeki; Tokumaru, Kayo; Miyamoto, Kazuaki; Sato, Takao; Shiratsuchi, Yuki; Oya, Masafumi; Koga, Hidenobu; Ihara, Eikichi; Nakamura, Kazuhiko |
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| 組織名 | Department of Gastroenterology, Aso Iizuka Hospital, Iizuka 820-8505, Japan.;kakahoshi2@aol.com.;Diagnosis Procedure Combination Coding Management Office, Aso Iizuka Hospital,;Iizuka 820-8505, Japan.;Department of Pathology, Aso Iizuka Hospital, Iizuka 820-8505, Japan.;Clinical Research Supportive Office, Aso Iizuka Hospital, Iizuka 820-8505, Japan.;Department of Medicine and Bioregulatory Science, Graduate School of Medical;Sciences, Kyushu University, Fukuoka 812-8582, Japan. |
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| Pubmed リンク | https://www.ncbi.nlm.nih.gov/pubmed/29085568/ |
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