| アブストラクト | The Clinical Practice Research Datalink (CPRD) is a repository of electronic medical records collected during routine primary care clinical practice in the UK, and is one of the most widely used sources of real-world data for healthcare research. Although CPRD provides access to comprehensive longitudinal patient records, the data does not fully capture diagnoses or outcomes occurring in secondary care and/or mortality. We provide here an overview of CPRD and the potential bias when using unlinked data in certain situations. Linkage of CPRD to other datasets can help to overcome these limitations. We discuss when to consider linkage to secondary care, disease-specific data sources or the official mortality data when conducting research using CPRD data. |
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| ジャーナル名 | European journal of epidemiology |
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| Pubmed追加日 | 2018/4/6 |
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| 投稿者 | McDonald, Laura; Schultze, Anna; Carroll, Robert; Ramagopalan, Sreeram V |
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| 組織名 | Centre for Observational Research and Data Sciences, Bristol-Myers Squibb,;Uxbridge, UB8 1DH, UK.;Real-World Evidence, Evidera, London, W6 8DL, UK.;Uxbridge, UB8 1DH, UK. sreeram.ramagopalan@bms.com. |
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| Pubmed リンク | https://www.ncbi.nlm.nih.gov/pubmed/29619668/ |
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