アブストラクト | Aim: Venous thromboembolism (VTE), which comprises deep vein thrombosis and pulmonary embolism, poses a global disease burden. Vitamin K antagonists have traditionally been the mainstay of treatment; however, the non-vitamin K oral anticoagulants (NOACs) are emerging as an alternative. The relative use of these treatment classes in the real world is unknown. Patients & methods: We performed a retrospective study using data from the UK Clinical Practice Research Datalink to understand VTE treatment patterns. Results: NOACs have unseated vitamin K antagonist as the main form of VTE patient treatment in England. Conclusion: The data highlight how comfortable physicians have become in using NOACs to treat VTE in England and it is likely that the increasing use of NOACs will continue. |
ジャーナル名 | Future cardiology |
Pubmed追加日 | 2019/3/26 |
投稿者 | Ramagopalan, Sreeram V; Carroll, Robert; Ulvestad, Maria; Mehmud, Faisal; Alikhan, Raza |
組織名 | Centre for Observational Research & Data Sciences, Bristol-Myers Squibb, Uxbridge;UB8 1DH, UK.;Medical Department, Bristol-Myers Squibb, 1366 Lysaker, Norway.;Medical Department, Bristol-Myers Squibb, Uxbridge UB8 1DH, UK.;Haemophilia & Thrombosis Centre, University Hospital Wales, Cardiff, UK. |
Pubmed リンク | https://www.ncbi.nlm.nih.gov/pubmed/30907131/ |