| アブストラクト | INTRODUCTION: Neuroleptics are the main antipsychotic agents used in psychiatric or medicine departments. The occurrence of hyperthermia, particularly in the context of the neuroleptic malignant syndrome, is a well-known side effect of these treatments. Conversely, the occurrence of hypothermia is less known from clinicians. CASE REPORT: We reported a 72-year-old woman, who presented with hypothermia associated with treatment with neuroleptics. This patient had no other medical comorbidities. Because of persistent hypothermia, altered consciousness and bradycardia, exhaustive diagnostic work-up as well as a prolonged hospitalization were necessary. The results of a review of the national French pharmacovigilance database showed that nearly a quarter (153/614) of drug-related hypothermia are attributed to psychotropic drug, mainly neuroleptics (99/153). CONCLUSION: A better awareness of hypothermia associated to neuroleptics should facilitate early diagnosis and reporting this side effect of neuroleptics. |
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| ジャーナル名 | La Revue de medecine interne |
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| Pubmed追加日 | 2013/10/26 |
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| 投稿者 | Huguet, B; Fongue, J; Chiche, L; Gilly, L; Pastor, M-J; Michelet, P; Rouby, F |
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| 組織名 | Service de medecine interne, CHU de la Conception, 147, boulevard Baille, 13005;Marseille, France.;Marseille, France. Electronic address: laurent.chiche@ap-hm.fr.;Service des urgences, CHU de la Conception, 147, boulevard Baille, 13005;Centre regional de pharmacovigilance Marseille-Provence-Corse, hopital;Sainte-Marguerite, AP-HM, 270, boulevard Saint-Marguerite, 13009 Marseille cedex;9, France. |
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| Pubmed リンク | https://www.ncbi.nlm.nih.gov/pubmed/24156974/ |
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