| アブストラクト | BACKGROUND: A scoping review to characterize the literature on the use of conversations in social media as a potential source of data for detecting adverse events (AEs) related to health products. METHODS: Our specific research questions were (1) What social media listening platforms exist to detect adverse events related to health products, and what are their capabilities and characteristics? (2) What is the validity and reliability of data from social media for detecting these adverse events? MEDLINE, EMBASE, Cochrane Library, and relevant websites were searched from inception to May 2016. Any type of document (e.g., manuscripts, reports) that described the use of social media data for detecting health product AEs was included. Two reviewers independently screened citations and full-texts, and one reviewer and one verifier performed data abstraction. Descriptive synthesis was conducted. RESULTS: After screening 3631 citations and 321 full-texts, 70 unique documents with 7 companion reports available from 2001 to 2016 were included. Forty-six documents (66%) described an automated or semi-automated information extraction system to detect health product AEs from social media conversations (in the developmental phase). Seven pre-existing information extraction systems to mine social media data were identified in eight documents. Nineteen documents compared AEs reported in social media data with validated data and found consistent AE discovery in all except two documents. None of the documents reported the validity and reliability of the overall system, but some reported on the performance of individual steps in processing the data. The validity and reliability results were found for the following steps in the data processing pipeline: data de-identification (n = 1), concept identification (n = 3), concept normalization (n = 2), and relation extraction (n = 8). The methods varied widely, and some approaches yielded better results than others. CONCLUSIONS: Our results suggest that the use of social media conversations for pharmacovigilance is in its infancy. Although social media data has the potential to supplement data from regulatory agency databases; is able to capture less frequently reported AEs; and can identify AEs earlier than official alerts or regulatory changes, the utility and validity of the data source remains under-studied. TRIAL REGISTRATION: Open Science Framework ( https://osf.io/kv9hu/ ). |
|---|
| ジャーナル名 | BMC medical informatics and decision making |
|---|
| Pubmed追加日 | 2018/6/15 |
|---|
| 投稿者 | Tricco, Andrea C; Zarin, Wasifa; Lillie, Erin; Jeblee, Serena; Warren, Rachel; Khan, Paul A; Robson, Reid; Pham, Ba'; Hirst, Graeme; Straus, Sharon E |
|---|
| 組織名 | Li Ka Shing Knowledge Institute of St. Michael's Hospital, 209 Victoria Street,;East Building, Toronto, ON, M5B 1W8, Canada. triccoa@smh.ca.;Epidemiology Division, Dalla Lana School of Public Health, University of Toronto,;6th Floor, 155 College St, Toronto, ON, M5T 3M7, Canada. triccoa@smh.ca.;East Building, Toronto, ON, M5B 1W8, Canada.;Department of Computer Science, University of Toronto, 10 King's College Road,;Toronto, ON, M5S 3G4, Canada.;Department of Geriatric Medicine, Faculty of Medicine, University of Toronto, 27;Kings College Circle, Toronto, ON, M5S 1A1, Canada. |
|---|
| Pubmed リンク | https://www.ncbi.nlm.nih.gov/pubmed/29898743/ |
|---|
