| アブストラクト | BACKGROUND: This study aimed to investigate medication prescriptions for patients with myelomeningocele (MMC) across different age groups, particularly in adulthood and after middle age. METHODS: The Japan Medical Data Center (JMDC) database, based on medical claims data, was utilized for this analysis. Patients were divided into 10-year age groups, and prescriptions for analgesics, anticonvulsants, psychotropic drugs, lifestyle disease-related drugs, drugs for urinary incontinence, and laxatives were examined. To compare the differences in the utilization of medications unrelated to lifestyle-related diseases across different age groups, the data was categorized into three age groups: 19 or under, 20-39, and 40 or older. RESULTS: Among the 556 MMC patients, the percentage of those regularly prescribed analgesics increased from 2.8% in patients </= 19 to 31.7% in patients 40 or older (p < 0.01). Psychotropic medication use also increased with age, rising significantly from 6.3% in patients </= 19 to 34.6% in patients 40 or older (p < 0.01). Patients with MMC showed an increasing trend in prescriptions for lifestyle-related disease medications compared to the normal control group. Notably, the percentage of patients in their 30 s taking hypertension medication was 4.9%, significantly higher than the 0.86% in the control group (p = 0.029). In their 40 s, 22.9% of MMC patients were prescribed hyperlipidemia medication, significantly higher than the 3.9% in the control group (p < 0.01). CONCLUSION: Comprehensive multidisciplinary support and follow-up are crucial to enhance the quality of life for MMC patients, with particular attention to pain management, psychological care, and treatment of lifestyle-related diseases. |
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| ジャーナル名 | Brain & development |
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| Pubmed追加日 | 2023/8/28 |
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| 投稿者 | Isozaki, Haruna; Nonaka, Masahiro; Komori, Yumiko; Ueno, Katsuya; Iwamura, Haruka; Miyata, Mayuko; Yamamura, Natsumi; Li, Yi; Takeda, Junichi; Nonaka, Yuichiro; Yabe, Ichiro; Zaitsu, Masayoshi; Nakashima, Kenji; Asai, Akio |
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| 組織名 | Department of Neurosurgery, Kansai Medical University, Hirakata, Osaka, Japan.;Electronic address: nonakam@hirakata.kmu.ac.jp.;Department of Neurosurgery, Jikei Medical University, Minato-Ku, Tokyo, Japan.;Department of Neurology, Hokkaido University, Sapporo, Hokkaido, Japan.;Center for Research of the Aging Workforce, University of Occupational and;Environmental Health, Japan.;National Hospital Organization, Matsue Medical Center, Matsue, Shimane, Japan. |
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| Pubmed リンク | https://www.ncbi.nlm.nih.gov/pubmed/37634963/ |
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