| アブストラクト | BACKGROUND: Evidence regarding the periprocedural safety of laser balloon (LB) catheter ablation for atrial fibrillation (AF) is scarce. OBJECTIVE: We aimed to investigate the periprocedural safety of LB ablation for AF compared with that of either radiofrequency or cryoballoon ablation using a nationwide claims database. METHODS: Patients who underwent catheter ablation for AF between 2018 and 2022 were identified using the Japanese Registry of All Cardiac and Vascular Diseases - Diagnosis Procedure Combination. The outcomes included in-hospital mortality, emergency 30-day readmission, common periprocedural complications, and a composite of complications. Outcomes were compared between the treatment groups in 2 separate propensity score-matched cohort: LB vs radiofrequency groups and LB vs cryoballoon groups. Mixed-effects logistic regression analysis was performed to calculate the odds ratios for the outcomes. RESULTS: Overall, 179,207 patients who underwent AF ablation were included. The incidence rate of periprocedural complications after LB ablation was 3.2%, including a 1.6% incidence of stroke. In propensity score-matched cohorts, LB ablation procedures were associated with a higher incidence of periprocedural complications compared with radiofrequency ablation procedures. Furthermore, LB ablation was associated with a higher incidence of stroke or transient ischemic attack than those after cryoballoon or radiofrequency ablation. No significant differences were observed in in-hospital deaths, other complications, or emergency readmissions between LB ablation and either radiofrequency or cryoballoon ablation. CONCLUSION: LB ablation was associated with a higher incidence of stroke compared with either cryoballoon or radiofrequency ablation. Most patients experiencing stroke after LB ablation were discharged home. |
| ジャーナル名 | Heart rhythm O2 |
| Pubmed追加日 | 2025/10/31 |
| 投稿者 | Kawase, Ken; Tonegawa-Kuji, Reina; Kanaoka, Koshiro; Sumita, Yoko; Miyamoto, Koji; Kusano, Kengo; Miyamoto, Yoshihiro |
| 組織名 | Department of Cardiovascular Medicine, National Cerebral and Cardiovascular;Center, Suita, Osaka, Japan.;Department of Advanced Cardiovascular Medicine, Graduate School of Medical;Sciences, Kumamoto University, Kumamoto, Kumamoto, Japan.;Department of Medical and Health Information Management, National Cerebral and;Cardiovascular Center, Suita, Osaka, Japan.;Open Innovation Center, National Cerebral and Cardiovascular Center, Suita,;Osaka, Japan. |
| Pubmed リンク | https://www.ncbi.nlm.nih.gov/pubmed/41169982/ |