| アブストラクト | BACKGROUND: Although the clinical application of robot-assisted esophagectomy (RE) has increased globally, its advantages over conventional thoracoscopic esophagectomy (TE) remain unclear. The aim of this study was to evaluate the short-term outcomes of RE compared with TE in patients with esophageal cancer in a nationwide cohort. METHODS: We retrospectively analyzed patients who underwent RE or TE for esophageal cancer between April 2018 and March 2022 by extracting data from the Diagnosis Procedure Combination, a Japanese national inpatient database. Instrumental variable analysis was employed to compare the short-term outcomes between the two groups. The primary outcomes included respiratory complications and unplanned reintubation. RESULTS: Among 7003 eligible patients from 69 hospitals, 1971 (28.1%) and 5032 (71.9%) underwent RE and TE, respectively. Respiratory complications, unplanned reintubation, and anastomotic leakage occurred in 1501 (21.4%), 475 (6.8%), and 904 patients (12.9%), respectively. Instrumental variable analysis demonstrated that the incidence of respiratory complications [odds ratio 0.65 (95% CI: 0.52-0.81) P < 0.001], unplanned reintubation [0.44 (0.31-0.62) P < 0.001], and anastomotic leakage [0.73 (0.56-0.94) P = 0.013] was significantly lower in the RE group compared with the TE group. CONCLUSIONS: RE was associated with better short-term outcomes, including fewer respiratory complications, unplanned reintubation, and anastomotic leakage, compared with TE. |
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| ジャーナル名 | Esophagus : official journal of the Japan Esophageal Society |
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| Pubmed追加日 | 2026/2/24 |
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| 投稿者 | Kurita, Daisuke; Hirano, Yuki; Ishiyama, Koshiro; Oguma, Junya; Matsui, Hiroki; Fushimi, Kiyohide; Kimura, Yuya; Aso, Shotaro; Yasunaga, Hideo; Seto, Yasuyuki; Daiko, Hiroyuki |
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| 組織名 | Division of Esophageal Surgery, National Cancer Center Hospital, 5-1-1 Tsukiji,;Chuo-Ku, Tokyo, 104-0045, Japan.;Course of Advanced Clinical Research of Cancer, Juntendo University Graduate;School of Medicine, Tokyo, Japan.;Department of Hepatobiliary-Pancreatic and Gastrointestinal Surgery,;International University of Health and Welfare School of Medicine, Chiba, Japan.;Department of Clinical Epidemiology and Health Economics, School of Public;Health, The University of Tokyo, Tokyo, Japan.;Department of Health Policy and Informatics, Institute of Science Tokyo Graduate;School, Tokyo, Japan.;Department of Health Services Research, Graduate School of Medicine, The;University of Tokyo, Tokyo, Japan.;Chuo-Ku, Tokyo, 104-0045, Japan. hdaiko@ncc.go.jp.;School of Medicine, Tokyo, Japan. hdaiko@ncc.go.jp. |
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| Pubmed リンク | https://www.ncbi.nlm.nih.gov/pubmed/41733764/ |
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