| アブストラクト | BACKGROUND: Echinococcosis is a rare but potentially life-threatening parasitic disease caused by Echinococcus species. In Japan, epidemiological data are mainly derived from notification-based surveillance, and large-scale nationwide analyses focusing on hospitalized patients remain limited. This study aimed to clarify the nationwide epidemiology and clinical characteristics of hospitalized patients with echinococcosis in Japan using an administrative database. METHODS: We conducted a retrospective nationwide study using the Japanese Diagnosis Procedure Combination database. Hospitalized patients diagnosed with echinococcosis between April 1, 2014, and March 31, 2021, were identified. Data on age, sex, geographic distribution, affected organs, comorbidities, treatments, Japan Coma Scale score, and length of hospital stay were extracted and analyzed. RESULTS: A total of 170 hospitalized patients coded for echinococcosis were included after exclusion of duplicate cases. The median age was 65.5 years, and 51% were male. Hepatic involvement was observed in 90% of patients, followed by pulmonary (4%), cutaneous (2%), cerebral (2%), and osseous (2%) involvement. Surgical treatment was frequently performed, including hepatectomy in 48% and cholecystectomy in 24% of patients, while albendazole therapy was administered in 21%. Most patients were from the Hokkaido region (85%), followed by the Kanto region (8%). The average annual number of hospitalized patients was approximately 24. CONCLUSION: Echinococcosis remains a clinically relevant parasitic disease in Japan, particularly in Hokkaido, and often requires hospitalization and surgical intervention. Nationwide administrative data provide valuable insights into the real-world clinical burden of echinococcosis. |
|---|
| ジャーナル名 | Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy |
|---|
| Pubmed追加日 | 2026/5/10 |
|---|
| 投稿者 | Nakamura, Kei; Ohkubo, Naoaki; Yamasaki, Kei; Tahara, Masahiro; Akata, Kentaro; Ikegami, Hiroaki; Nishida, Chinatsu; Okawara, Makoto; Fujino, Yoshihisa; Matsuda, Shinya; Fushimi, Kiyohide; Mukae, Hiroshi; Yatera, Kazuhiro |
|---|
| 組織名 | Department of Respiratory Medicine, University of Occupational and Environmental;Health, Japan, Kitakyushu, Japan.;Department of Environmental Epidemiology, Institute of Industrial Ecological;Sciences, University of Occupational and Environmental Health, Japan, Kitakyushu,;Japan.;Department of Respiratory Medicine, Wakamatsu Hospital of the University of;Occupational and Environmental Health, Japan, Kitakyushu, Japan. Electronic;address: yamasaki@med.uoeh-u.ac.jp.;Division of Infection Control and Prevention, University of Occupational and;Environmental Health, Japan, Kitakyushu, Japan.;Department of Environmental Health Engineering, Institute of Industrial;Ecological Sciences, University of Occupational and Environmental Health, Japan,;Kitakyushu, Japan.;Department of Preventive Medicine and Community Health, University of;Occupational and Environmental Health, Japan, Kitakyushu, Japan.;Department of Nursing, Fukuoka International University of Health and Welfare,;Fukuoka, Japan.;Department of Health Policy and Informatics, Institute of Science Tokyo, Tokyo,;Department of Respiratory Medicine, Nagasaki University Graduate School of;Biomedical Sciences, Nagasaki, Japan. |
|---|
| Pubmed リンク | https://www.ncbi.nlm.nih.gov/pubmed/42106069/ |
|---|
