論文・技術情報追加のお知らせ

1. Tacrolimus Related Acute Pancreatitis: An Observational, Retrospective, Pharmacovigilance Study.

タクロリムスと急性膵炎の安全性に関する懸念

対象DB：FAERS

2. Risk of VMAT2 inhibitors on suicidality and parkinsonism: report utilizing the United States Food and Drug Administration adverse event reporting system.

VMAT2阻害剤の安全性を評価

対象DB：FAERS

3. Post-marketing safety concerns of sotorasib: A disproportionality analysis based on FDA adverse event reporting system.

ソトラシブ関連の副作用をFAERSで評価

対象DB：FAERS

4. Safety analysis of Oseltamivir and Baloxavir Marboxil after market approval: a pharmacovigilance study based on the FDA adverse event reporting system.

オセルタミビルとバロキサビル マルボキシルの安全性調査

対象DB：FAERS

5. Safety of cardiovascular disease drugs approved between 2014 and 2021 in the US: a pharmacovigilance analysis.

2014年から2021年に承認された心血管疾患治療薬の安全性調査

対象DB：FAERS

6. Dasatinib-induced pleural effusions, pericardial effusion and pulmonary arterial hypertension: a case report.

12歳のCML患者、ダサチニブ治療中に重篤な副作用

対象DB：FAERS

7. Endocrine system-related adverse events associated with PD-1/PD-L1 inhibitors: data mining from the FDA adverse event reporting system.

PD-1/PD-L1阻害薬使用後の内分泌系副作用に男性65歳以上が注意が必要

対象DB：FAERS

8. Contribution of aldehyde oxidase to methotrexate-induced hepatotoxicity: In Vitro and pharmacoepidemiological approaches.

AOX阻害はMTX誘発性肝障害を増強

対象DB：FAERS

9. Myocardial Infarction in Chronic Myeloid Leukemia: Results from Nationwide Readmission Database.

CML患者と非CML患者のPCI後の予後は類似

対象DB：FAERS

10. Comparators in Pharmacovigilance: A Quasi-Quantification Bias Analysis.

自然発生報告におけるバイアス低減には適切な比較薬が不明

対象DB：CVAR,FAERS

11. Antipsychotic-Related DRESS Syndrome: Analysis of Individual Case Safety Reports of the WHO Pharmacovigilance Database.

DRESS症候群と抗精神病薬の関連はクロザピン以外でもみられる

対象DB：VigiBase

12. Current Clinical Practice of Laboratory Testing of the Hemostasis and Coagulation System in Patients with Sepsis: A Nationwide Observational Study in Japan.

日本における敗血症患者の凝固機能マーカーの実際の測定頻度が低い

対象DB：DPC

13. Foot and ankle problems in children and young people: a population-based cohort study.

英国における10?14歳の男子における足首および足の問題の診療が多い

対象DB：CPRD

14. Dipeptidyl Peptidase-4 Inhibitors and the Risk of Gallbladder and Bile Duct Disease Among Patients with Type 2 Diabetes: A Population-Based Cohort Study.

DPP-4阻害剤使用は、胆嚢および胆管疾患のリスク増加と関連

対象DB：CPRD

15. Risk equations for prosthetic joint infections (PJIs) in UK: a retrospective study using the Clinical Practice Research Datalink (CPRD) AURUM and GOLD databases.

UKの電子健康記録からPJIのリスクモデルを開発

対象DB：CPRD

16. Accuracy of the recording of pneumonia events in English electronic healthcare record data in patients with chronic obstructive pulmonary disease.

COPD患者の主治医診療所での肺炎診断の精度は低く、入院後の肺炎も記録が不十分

対象DB：CPRD

17. Factors associated with non-fatal heart failure and atrial fibrillation or flutter within the first 30 days post COPD exacerbation: a nested case-control study.

COPD悪化後30日以内に心不全や心房細動の入院が増加

対象DB：CPRD