論文・技術情報追加のお知らせ

1. Immune Checkpoint Inhibitor (ICI) Induced Sinonasal Disease: Review of Literature and FDA Database.

免疫チェックポイント阻害剤による鼻副作用は未認識。研究と認識向上が必要

対象DB：FAERS

2. Adverse events related to neuromuscular blocking agents: a disproportionality analysis of the FDA adverse event reporting system.

神経筋遮断薬の副作用をFAERSで分析。新たな副作用も発見

対象DB：FAERS

3. A real-world pharmacovigilance study of FDA adverse event reporting system (FAERS) events for sunitinib.

スニチニブの副作用をFAERSで分析。予期しない副作用も確認

対象DB：FAERS

4. Signal mining and analysis of trifluridine/tipiracil adverse events based on real-world data from the FAERS database.

トリフルリジン/ティピラシルの副作用をFAERSで分析

対象DB：FAERS

5. An investigation of broad-spectrum antibiotic-induced liver injury based on the FDA Adverse Event Reporting System and retrospective observational study.

タゾバクタム/ピペラシリンとメロペネムによる肝障害のリスク要因を調査

対象DB：FAERS

6. Lost needles, pads and where to find them.

神経外科手術での「ニアミス」発生要因を分析し、安全対策を提案

対象DB：FAERS

7. Real-world Disproportionality Analysis of the FDA Adverse Event Reporting System (FAERS) Database for Asciminib.

アスチミニブの副作用を評価し、新たな有害事象を特定

対象DB：FAERS

8. Adverse event profile of memantine and donepezil combination therapy: a real-world pharmacovigilance analysis based on FDA adverse event reporting system (FAERS) data from 2004 to 2023.

ドネペジルとメマンチンの併用療法に関する副作用の分析結果を報告

対象DB：FAERS

9. Signal mining of adverse reactions in the antiemetic drug ondansetron during pregnancy: A real-world analysis of the FDA adverse event reporting system (FAERS).

オンダンセトロンは妊娠中に多くの副作用が報告されている

対象DB：FAERS

10. Post-marketing safety concerns with montelukast: A pharmacovigilance study based on the FDA adverse event reporting system.

モンテルカストは主に若年層で精神的副作用が多く報告されている

対象DB：FAERS

11. Tinnitus after COVID-19 vaccination: Findings from the vaccine adverse event reporting system and the vaccine safety datalink.

COVID-19ワクチン後の耳鳴りリスクは増加しないと報告

対象DB：FAERS,VAERS

12. Signal mining and gender differences analysis of adverse events in NMIBC treatment with gemcitabine and BCG bladder instillation based on the FAERS database.

ジェムシタビンとBCGで副作用に性差が見られた

対象DB：FAERS,VAERS

13. Seriousness and outcomes of reported adverse drug reactions in old and new antiseizure medications: a pharmacovigilance study using EudraVigilance database.

抗てんかん薬の副作用報告では、古い薬の方が深刻なケースが多かった

対象DB：EudraVigilance

14. SARS-CoV-2 mRNA vaccine-related myocarditis and pericarditis: An analysis of the Japanese Adverse Drug Event Report database.

日本でのSARS-CoV-2 mRNAワクチンは心筋炎・心膜炎と関連

対象DB：JADER

15. Effects of early surgery for cervical fracture dislocation on 30-day mortality using the Japanese Diagnosis Procedure Combination database.

頸椎骨折脱臼の早期手術は30日以内の死亡率が高い

対象DB：DPC

16. Trends, costs, and complications associated with after-hours surgery and unscheduled hospitalization in spinal surgery.

日本の脊椎手術は増加中で、特に時間外手術と緊急入院が増加し、合併症と費用も増加

対象DB：DPC

17. Trimethoprim-sulfamethoxazole combined with echinocandins versus trimethoprim-sulfamethoxazole alone for Pneumocystis pneumonia in patients without human immunodeficiency virus infection: A nationwide retrospective cohort study.

非HIV患者のPCPで、エキノカンジン併用療法は死亡率改善に寄与しない

対象DB：DPC

18. Annual trends in atypical haemolytic uremic syndrome management in Japan and factors influencing early diagnosis and treatment: a retrospective study.

日本のaHUS診断と早期治療は進展がなく、早期認識が重要

対象DB：DPC

19. Implementation status of comprehensive geriatric assessment among older inpatients: A nationwide retrospective study.

日本では高齢者総合評価（CGA）が増加中も地域差が大きい

対象DB：DPC

20. Stroke Research Using Administrative Claims Database in Japan: A Narrative Review.

日本の脳卒中研究で行政データベースの利用は増加中だが、限界も多い

対象DB：DPC,NDB

21. Body Mass Index and Outcomes in Patients with Takotsubo Syndrome: A Nationwide Retrospective Cohort Study.

タコツボ症候群では、BMIが低いほど入院死亡率が高い

対象DB：DPC

22. Impact of new antifungal medications on onychomycosis prescriptions and costs in Japan: A nationwide claims database study.

日本の爪白癬治療で外用薬が多く、医療費が増加

対象DB：NDB

23. Impact of the COVID-19 Pandemic on Hypofractionated Radiation Therapy Use for Breast Cancer in Japan: A Nationwide Study.

COVID-19で日本の乳がん放射線治療は一時的に増加したが、持続的ではなかった

対象DB：NDB

24. Regional disparities in primary cesarean delivery rates in Japan: the role of obstetrician availability.

日本のPCD率は地域差が大きく、産科医不足が影響

対象DB：NDB

25. Hyperkalemia Burden and Treatment Pathways in Patients with CKD: Findings From the DISCOVER CKD Retrospective Cohort.

HK患者の治療経路は日英で異なり、日本ではカリウム結合剤が多用される

対象DB：CPRD,MDV

26. Levothyroxine treatment of subclinical hypothyroidism and the risk of adverse cardiovascular events.

レボチロキシン治療でSCH患者の心血管リスクがわずかに減少

対象DB：CPRD

27. Effects of antimicrobial exposure on the risk of Parkinson's disease.

抗菌薬使用がパーキンソン病リスクに影響、ペニシリンは低下、抗真菌薬は上昇

対象DB：CPRD

28. Prescribing Cascades of Loop Diuretics and Anti-vertigo Drugs Following Treatment with Gabapentinoids and Benzodiazepines: Prescription Sequence Symmetry Analysis of a Large-Scale Claims Database Including Japanese Older Adults.

GBPやBZ使用後に浮腫で利尿薬が過剰処方されるリスクあり

対象DB：DeSC