論文・技術情報追加のお知らせ

1. Bisphosphonate- and disumab-related gingival disorders: case analysis from the U.S. Food and Drug Administration Adverse Event Reporting System.

ビスホスホネートとデノスマブは歯肉障害と関連があり、特にパミドロネートに強い関連あり

対象DB：FAERS

2. Analysis of publicly available adverse events reported for pediatric patients treated with Janus kinase inhibitors.

JAKiの副作用は成人と小児で異なり、小児では血液・リンパ系の障害が多い

対象DB：CVAR,FAERS

3. A real-world disproportionality analysis of Baloxavir Marboxil: post-marketing pharmacovigilance data.

バロキサビルの新たな副作用シグナルとして肺炎や意識喪失などを確認

対象DB：FAERS

4. Therapeutic failure reported with HIV long-acting injectables: An analysis of the FDA Adverse Event Reporting System from 2021 to 2024.

CAB/RPV使用時の主な副作用は治療失敗と投与忘れ

対象DB：FAERS

5. Post-marketing drug safety surveillance of enfortumab vedotin: an observational pharmacovigilance study based on a real-world database.

エンフォツマブ・ヴェドチンの主な副作用は皮膚障害と末梢神経障害

対象DB：FAERS

6. Comparative analysis of adverse event risks in breast cancer patients receiving pembrolizumab combined with paclitaxel versus paclitaxel monotherapy: insights from the FAERS database.

ペムブロリズマブ＋パクリタキセルは副作用リスク増加

対象DB：FAERS

7. CAR-T therapy pulmonary adverse event profile: a pharmacovigilance study based on FAERS database (2017-2023).

CAR-T療法に伴う肺関連有害事象をFAERSで分析

対象DB：FAERS

8. Ocular adverse events associated with antibody-drug conjugates in oncology: a pharmacovigilance study based on FDA adverse event reporting system (FAERS).

抗体薬物複合体（ADCs）の眼毒性リスクをFAERSで分析

対象DB：FAERS

9. What is the validity of the Federal Adverse Event Reporting System in contemporary clinical research?

FAERSの現代の臨床研究における有効性

対象DB：FAERS

10. Antibody-drug conjugates-related interstitial lung diseases: data mining of the FAERS database.

抗体薬物複合体（ADC）使用で間質性肺疾患のシグナルが強い

対象DB：FAERS

11. Subgroup disproportionality analysis of dementia-related adverse events with sacubitril/valsartan across geographical regions.

サクビトリル/バルサルタンは北米で認知症関連AEリスクが高い

対象DB：FAERS,KAERS

12. Drugs Associated with Urinary Retention Adverse Reactions: A Joint Analysis of FDA Adverse Event Reporting System and Mendelian Randomization.

尿閉に関連する薬物としてアムロジピンが特定された

対象DB：FAERS

13. Mortality and Serious Adverse Events Associated With Glucagon-Like Peptide-1 Receptor Agonists: A Pharmacovigilance Study Using the FDA Adverse Event Reporting System.

GLP-1受容体作動薬の死亡リスクと重大副作用が確認された

対象DB：FAERS

14. Disproportionality Analysis of Osimertinib-related Adverse Events in Elderly Patients Using the Japanese Pharmacovigilance Database.

オシメルチニブは70歳以上で心筋症リスクが高い

対象DB：JADER

15. SGLT2 Inhibitor and Urinary Tract Infection in Men at Risk for Voiding Dysfunction: A VigiBase Analysis.

SGLT2阻害剤は男性、特に高齢者で尿路感染リスクが高い

対象DB：VigiBase

16. Clozapine may consistently protect from suicidal behaviors while other antipsychotics may lack a specific protective effect: a comprehensive VigiBase study interpreted in the context of the prior literature.

クロザピンは自殺リスクに強い効果を示すが、過剰摂取の致死性も高い

対象DB：VigiBase

17. Disproportionality analysis of cardiac adverse events associated with lenvatinib using the Japanese Adverse Drug Event Report database.

レンバチニブ使用後の心疾患リスクと発症タイミングを検討

対象DB：JADER

18. Factor affecting severe atherothrombotic cerebral infarction in patients with type 2 diabetes mellitus: Large-scale claim database analysis of Japan.

脂質管理で糖尿病患者の重症脳梗塞悪化を予防可能

対象DB：DPC,MDV

19. Rheumatoid arthritis increases complication risks in elderly hip fracture patients.: A Japanese nationwide medical claims database study.

RA患者は股関節骨折後、肺炎や肺塞栓の合併症が増加

対象DB：DPC

20. Comparison of Clinical Outcomes in Patients with Acute Lower Limb Ischaemia Undergoing Endovascular Therapy and Open Surgical Revascularisation: A Large Scale Analysis in Japan.

急性肢虚血治療では、PAD以外はOSRがEVTより有効

対象DB：DPC

21. Increased early complications after total hip arthroplasty compared with hemiarthroplasty in older adults with a femoral neck fracture.

THAは術後合併症リスクが高く、入院費も増加

対象DB：DPC

22. A cross-national investigation of CT, MRI, PET, mammography, and radiation therapy resources and utilization.

日本はCT・MRI普及率が高いが、放射線専門職が不足

対象DB：NDB

23. The age of death in Japanese patients with type 2 and type 1 diabetes: A descriptive epidemiological study.

糖尿病患者は非糖尿病患者より平均寿命が2.6年短い

対象DB：NDB

24. Is it possible to identify populations experiencing material disadvantage in primary care? A feasibility study using the Clinical Practice Research Database.

英国の医療記録から物質的困窮を測定する手法が不十分

対象DB：CPRD

25. The association of type 2 diabetes-related characteristics with fracture risk at different sites.

糖尿病の罹病期間や血糖値が骨折リスクに関連

対象DB：CPRD

26. Targeted precision cryotherapy for acne vulgaris.

精密冷凍療法がニキビを改善し、安全かつ満足度も高い治療法であることが示された

対象DB：KAERS