論文・技術情報追加のお知らせ

1. Cardiac adverse events associated with statins in myocardial infarction patients: a pharmacovigilance analysis of the FDA Adverse Event Reporting System.

MI患者におけるスタチンの心臓副作用は確認されず

対象DB：FAERS

2. Comprehensive analysis of VEGF/VEGFR inhibitor-induced immune-mediated hypertension: integrating pharmacovigilance, clinical data, and preclinical models.

VEGF阻害剤の高血圧に関する免疫機序比較

対象DB：FAERS

3. Adverse drug reaction signals mining comparison of amiodarone and dronedarone: a pharmacovigilance study based on FAERS.

アミオダロンとドロネダロンのADRプロファイル比較

対象DB：FAERS

4. ADR-DQPU: A Novel ADR Signal Detection Using Deep Reinforcement and Positive-Unlabeled Learning.

ADRシグナル検出の新手法「ADR-DQPU」、精度向上

対象DB：FAERS

5. Adverse events associated with herbal medicine products reported in the Korea Adverse Event Reporting System from 2012 to 2021.

韓国の生薬製品の副作用データ分析

対象DB：FAERS,KAERS

6. Adverse events associated with aromatase inhibitors: An Analysis of Real-World Datasets and drug-gene interaction network.

アロマターゼ阻害薬に関する安全性問題が明らかに

対象DB：FAERS

7. Exploring and comparing renal adverse effects between PARP inhibitors based on a real-world analysis of post-marketing surveillance data.

PARPi治療は高齢者で腎障害リスクが高い

対象DB：FAERS

8. beta-Blockers and Asthma: Surprising Findings from the FAERS Database.

喘息患者へのβ遮断薬選択は慎重に

対象DB：FAERS

9. Exploring suicidal and self-injurious behaviors signal strength of biologics in treating psoriasis or psoriatic arthritis: A 10-year real-world pharmacovigilance analysis using the FDA Adverse Event Reporting System database.

生物学的製剤の自殺・自傷行為に関する分析

対象DB：FAERS

10. Serious adverse events reported with benzimidazole derivatives: A disproportionality analysis from the World Health Organization's pharmacovigilance database.

ベンジミダゾール誘導体の重篤な副作用に関する信号

対象DB：VigiBase

11. Reporting of late-onset immune-related adverse events with immune checkpoint inhibitors in VigiBase.

免疫チェックポイント阻害薬の遅発性免疫関連副作用に関する研究

対象DB：VigiBase

12. Patient-Initiated Nationwide Survey on Testing for Actionable Oncogenic Drivers in Non-Small Cell Lung Cancer in Japan.

日本で進行非小細胞肺癌の遺伝子検査率が増加

対象DB：DPC

13. Iterative random forest-based identification of a novel population with high risk of complications post non-cardiac surgery.

非心臓手術で低LDL-Cと脳卒中歴が高リスク

対象DB：JMDC

14. Evaluating the effects of 5-aminosalicylic acid on tofacitinib treatment in ulcerative colitis.

低用量トファシチニブで5-ASA併用が再発リスク低減

対象DB：MDV

15. Cohort studies on 71 outcomes among people with atopic eczema in UK primary care data.

アトピー性湿疹は多様な健康リスク増と関連

対象DB：CPRD

16. Comparative risk of mortality in new users of prescription opioids for noncancer pain: results from the International Pharmacosurveillance Study.

強オピオイド使用で非がん疼痛患者の死亡リスク増加

対象DB：CPRD

17. Identifying and Predicting Risk for Hospital Admission among Patients with Parkinsonism.

パーキンソン患者は肺炎などで緊急入院リスク増

対象DB：CPRD

18. Antidepressant prescribing inequalities in people with comorbid depression and type 2 diabetes: A UK primary care electronic health record study.

2型糖尿病患者は抗うつ薬処方率が低く、不平等が示唆

対象DB：CPRD

19. Tuberculosis and increased incidence of cardiovascular disease: Cohort study using US and UK health records.

結核患者は特に診断前後にCVDリスク増

対象DB：CPRD

20. Clinical Burden and Healthcare Resource Utilization Associated With Managing Transfusion-dependent beta-Thalassemia in England.

英国TDT患者は高死亡率と医療負担が大きい

対象DB：CPRD

21. What happens between first symptoms and first acute exacerbation of COPD - observational study of routine data and patient survey.

COPD診断と管理の改善傾向と課題を調査

対象DB：CPRD

22. Nationwide Epidemiology and Outpatient Healthcare Resource Use of Children with Respiratory Syncytial Virus from 2005 to 2021.

日本の乳幼児におけるRSV感染症の流行と外来医療資源の利用変化の調査

対象DB：DeSC