論文・技術情報追加のお知らせ

1. Adverse drug reactions related to methotrexate: a real-world pharmacovigilance study using the FAERS database from 2004 to 2024.

メトトレキセートの安全性プロファイルの包括的分析

対象DB：FAERS

2. Characteristics of Adverse Events and Clinical Risks of Omaveloxolone Based on FAERS Data.

フリードライヒ運動失調症治療薬の安全性評価

対象DB：FAERS

3. Lansoprazole identified as a prophylactic agent for oxaliplatin-induced peripheral neuropathy using integrated in silico, in vitro, and in vivo analyses.

オキサリプラチン誘発性神経障害の予防治療研究

対象DB：FAERS,JADER

4. Depression and suicide/self-injury signals for weight loss medications: A disproportionality analysis of semaglutide, liraglutide, and tirzepatide in FAERS database.

GLP-1RAと精神障害リスクの関連性評価

対象DB：FAERS

5. Pharmacovigilance insights into antibody-drug conjugates: a multi-database analysis of adverse events in leukemia treatment.

複数DBからの白血病治療薬の副作用シグナル分析

対象DB：FAERS,JADER

6. A real-world pharmacovigilance study of belzutifan in renal cell carcinoma and von Hippel-Lindau disease: insights from the FDA adverse event reporting system database.

ベルズチファン関連副作用のRWD評価

対象DB：FAERS

7. Comparison of safety of lecanemab and aducanumab: a real-world disproportionality analysis using the FDA adverse event reporting system.

アルツハイマー薬の性別差を含む安全性評価

対象DB：FAERS

8. Emerging cardiovascular toxicity associated with CDK4/6 inhibitors: real-world insights from the FDA adverse event reporting system.

CDK4/6阻害剤と心血管有害事象の分析

対象DB：FAERS

9. A real-world study based on the FAERS database evaluating adverse drug reactions in three amphotericin B lipid formulations.

アムホテリシンB製剤の安全性評価

対象DB：FAERS

10. Risk of musculoskeletal disorders associated with Bruton's tyrosine kinase inhibitors: a disproportionality analysis of FAERS database and meta-analysis.

BTK阻害剤と筋骨格系障害の関連分析

対象DB：FAERS

11. Efficacy of Apolipoprotein A-1 Infusion on Coronary Atherosclerosis Postacute Coronary Syndrome: A Network Meta-Analysis of Randomized Controlled Trials.

ApoA1投与による動脈石灰化の減少分析

対象DB：JADER

12. Identifying New Candidate Predictors of Mortality in Japanese Patients with Severe Drug Eruptions.

SJS/TEN死亡予測モデルの開発

対象DB：JADER

13. Atypical Femoral Fracture in Patients With Metastatic Bone Tumors: An Analysis Based on the Japanese Adverse Drug Event Reaction Database (JADER).

デノスマブ関連大腿骨骨折の研究

対象DB：JADER

14. Cannabinoids and Adverse Convulsive Effects: A Pharmacovigilance and Addictovigilance Analysis of Cases Reported in France.

カンナビノイド使用後の発作リスク特定

対象DB：EudraVigilance

15. Impact of Brexit on Pharmaceutical Regulations: EMA vs. MHRA.

Brexitが医薬品規制環境に大きな変化をもたらす

対象DB：EudraVigilance

16. Comedications Associated with Immune-Related Adverse Events from Immune-Checkpoint Inhibitors.

ICI治療中の併用薬が免疫関連有害事象に影響を与える可能性を評価

対象DB：VigiBase

17. Opioid use in postoperative pain management of pediatric appendectomy patients in Japan.

小児虫垂炎手術後のオピオイド使用を評価

対象DB：DPC

18. Prognostic impact of the timing of antihypertensive medication initiation for hypertension detected at health screening on primary prevention of adverse cardiovascular events: Age-stratified real-world data analysis.

高齢者での高血圧治療開始タイミングと心血管イベント予防の影響を検証

対象DB：JMDC

19. Changes in seeking smoking cessation therapy among Japanese employees and their families: a possible role for the dissemination of heated tobacco products (HTPs).

加熱式たばこ製品の普及が喫煙行動に与える影響を分析

対象DB：JMDC

20. Risk of postcolonoscopy colorectal cancer following single-session endoscopic polypectomy: a retrospective cohort study using nationwide claims data.

大腸がん予防のための異なるポリープ切除戦略の影響を調査

対象DB：JMDC

21. Seasonal Variation and Meteorological Correlates of Botulinum Toxin Injections for Axillary Hyperhidrosis in Japan: A Retrospective Analysis.

日本における腋窩多汗症注射の季節的違いと気象条件の関係を分析

対象DB：NDB

22. Risk factors for recurrent attacks of wheeze in preschool children: a population-based cohort study in England.

幼児の再発性喘息発作のリスク要因の研究

対象DB：CPRD

23. Temporal trends in primary care-recorded psychiatric diagnoses and psychotropic medication prescribing among children and young people in the UK: a population-based study.

若年層の精神疾患の発症率と向精神性薬処方の時間的変動

対象DB：CPRD

24. Glucose Control, Sulfonylureas, and Insulin Treatment in Older Adults With Type 2 Diabetes and Risk of Falls and Fractures: An Observational Study.

高齢型2糖尿病患者の転倒・骨折リスクと血糖コントロールの関連性

対象DB：CPRD

25. Development and external validation of a risk prediction score (DASHI) for cardiovascular events following acute respiratory infections: derivation and validation retrospective cohort study.

急性呼吸器感染後の心血管イベントリスク予測ツールの開発

対象DB：CPRD

26. GP consultations for respiratory tract infections in children aged

COVID-19後の小児呼吸器感染症のGP受診率の変動を分析

対象DB：CPRD

27. Association of Lean Mass Index with a risk of incident stroke: a Nationwide epidemiological cohort study.

LMIが高いほど、脳卒中のリスクが低下

対象DB：DeSC