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論文・技術情報追加のお知らせ

• 論文・技術情報追加のお知らせ

  2025年11月10日～2025年11月15日の間に収集した論文情報を追加しました。

  1. Signal mining and analysis of influencing factors for adverse events of Nivolumab and Cetuximab in the treatment of head and neck cancer based on the US FAERS database.

  ニボルマブは免疫毒性、セツキシマブは皮膚代謝毒性が特徴

  対象DB：FAERS

  2. A real-world drug safety surveillance study from the FAERS database of hepatocellular carcinoma patients receiving durvalumab in combination with tremelimumab.

  デュルバルマブ＋トレメリムマブで免疫関連毒性多発

  対象DB：FAERS

  3. Pharmacovigilance analysis of myopathy associated with azoles and nonstatins interactions based on US FAERS database.

  非スタチン併用でもアゾール系で筋症リスク増

  対象DB：FAERS

  4. Mining and analysis of drug-induced shock adverse reactions: A comprehensive pharmacovigilance study based on the US FAERS database.

  多薬剤でショック関連リスクを大規模解析

  対象DB：FAERS

  5. Comparative Renal Safety of Tirzepatide and Semaglutide: An FDA Adverse Event Reporting System (FAERS)-Disproportionality Study.

  セマグルチドでAKI報告多く注意が必要

  対象DB：FAERS

  6. Dysphagia after COVID-19 Vaccination: A Report of Two Cases.

  COVID-19ワクチン後の嚥下障害2例を報告

  対象DB：FAERS,VAERS

  7. A real-world pharmacovigilance study of FDA adverse event reporting system (FAERS) for therapeutic radiopharmaceuticals.

  放射性医薬品の有害事象をFAERSで解析

  対象DB：FAERS

  8. Safety of penicillamine and trientine in the treatment of Wilson's disease: An analysis of the FDA Adverse Event Reporting System (FAERS) database.

  WD治療薬の有害事象をFAERSで解析

  対象DB：FAERS

  9. Association between immune check point inhibitors and digestive system inflammatory adverse reactions: evidence from pharmacovigilance analysis and systematic review.

  PD-1とCTLA-4阻害薬で消化炎症の発現傾向が異なる

  対象DB：FAERS

  10. Drug-induced enterocolitis syndrome with amoxicillin-containing products: A review of cases reported to the FDA adverse event reporting system and published literature.

  アモキシシリンでDIES発症例を整理し特徴を報告

  対象DB：FAERS

  11. Real-world safety profile of sonidegib: a disproportionality analysis based on the FDA adverse event reporting system.

  ソニデギブ治療で感染症など新たな副作用示唆

  対象DB：FAERS

  12. Causal Influences of Micronutrients on Anxiety: Insights From an Observational and Mendelian Randomization Analysis.

  ビタミンC・Mg・Seが不安症に保護的可能性

  対象DB：FAERS

  13. Vascular and neurological toxicity profile of Sipuleucel-T: a large-scale real world pharmacovigilance study.

  Sipuleucel-Tで脳心血管系の特定リスク増大

  対象DB：FAERS

  14. Long-term trends in reporting of cardiac adverse drug reactions to COVID-19 vaccines - an exploratory analysis of the EudraVigilance database.

  COVID-19ワクチン後の重篤心障害報告は時期で変動

  対象DB：EudraVigilance

  15. Analysis of suspected serious adverse drug reactions reported with traditional medicines from the United Nations Asia region in WHO vigibase.

  伝統薬でも重篤な有害事象が報告され注意必要

  対象DB：VigiBase

  16. Suitability of Japanese Medical Databases for Studies on Infant Outcomes After Maternal Drug Exposure: An Evaluation Based on Core Data Elements.

  日本の母子データベースは周産期研究に有用

  対象DB：DeSC,JADER

  17. Increased postoperative complication risk in elderly hip fracture patients with cerebrovascular disorders: A propensity score-matched nationwide cohort study.

  脳血管障害は高齢者の術後合併症増加

  対象DB：DPC

  18. Evaluating In-Hospital Safety and Perioperative Costs of Total Hip Arthroplasty in Super-Elderly Patients: A Nationwide Propensity Score-Matched Analysis in Japan.

  超高齢者THAは僅かに合併症増も安全

  対象DB：DPC

  19. Computer-assisted total hip arthroplasty reduces early complications based on Japanese nationwide medical claims data.

  CA-THAは脱臼など減少も骨折リスク増大

  対象DB：DPC

  20. Temporal Trends in Utilization of Transvenous Lead Extractions Among Cardiac Implantable Electronic Device Infections.

  CIED感染でTLE不足、非認定病院で未実施多い

  対象DB：DPC

  21. In-hospital outcomes of lacosamide versus levetiracetam for early adjunctive treatment of status epilepticus: A Nationwide Japanese retrospective cohort study.

  LCMはSE早期治療で予後改善の可能性

  対象DB：DPC

  22. Postoperative risk profile in elderly hip fracture patients undergoing chronic hemodialysis based on a nationwide database investigation.

  透析患者の大腿骨骨折術後転帰は不良

  対象DB：DPC

  23. Outcome, Process, Utilization, and Cost Measurements of Patients Admitted to the ICU in Hospitals With Vs. Without an Intermediate Care Unit: A Nationwide Inpatient Database Study.

  IMCU併設ICUは患者予後改善と効率化に寄与

  対象DB：DPC

  24. Medical cost of postoperative delirium after highly invasive cancer resection: a prospective cohort study.

  重度術後せん妄は医療費増大を招き予防が重要

  対象DB：DPC

  25. Factors associated with the incidence of aspiration pneumonia during hospitalization in older adults admitted for non-respiratory diseases in an acute-care hospital: a retrospective cohort study.

  高齢入院患者の誤嚥性肺炎は嚥下障害や虚弱が主要因

  対象DB：DPC

  26. Trends in radiotherapy use and implementation challenges among patients with cervical cancer: a multicenter study in Osaka, Japan.

  大阪で子宮頸がん放射線治療が増加し施設間差も大きい

  対象DB：DPC

  27. Epidemiology and Clinical Outcomes of Meningococcal Infections in Japan: A Nationwide Inpatient Database Study from 2010 to 2023.

  日本の髄膜炎菌感染は重症度と併存症が予後を左右

  対象DB：DPC

  28. Treatment patterns and outcomes in patients with steroid-dependent ulcerative colitis in Japan: a claims database study.

  日本ではUCのステロイド依存治療が多く最適化が必要

  対象DB：JMDC

  29. Trends in Laparoscopic and Robot-Assisted Surgery in Gynecology: A 10-Year Nationwide Study in Japan.

  日本で腹腔鏡・ロボ手術が近年大幅に増加している

  対象DB：NDB

  30. Robotic-assisted versus minimally invasive mitral valve repair: a claims data analysis of clinical and cost outcomes.

  ロボ補助と小切開の僧帽弁修復は安全性と費用が概ね同等との報告

  対象DB：MDV

  31. Estimating 10-Year Cardiovascular Disease Risk in Primary Prevention Using UK Electronic Health Records and a Hybrid Multitask BERT Model: Retrospective Cohort Study.

  EHR文書と構造データ統合しCVD10年リスクを高精度に予測

  対象DB：CPRD

  32. RecUrrent Intra-articular Corticosteroid injections in Osteoarthritis: the RUbICOn mixed-methods study.

  英国での関節内ステロイド注射の安全性と長期効果を詳しく検証

  対象DB：CPRD

  33. Developing and validating a clinical prediction model to predict epilepsy-related emergency department attendance, hospital admission, or death: A cohort study protocol.

  てんかん患者の入院・死亡を予測する新モデルの開発と検証研究

  対象DB：CPRD

  34. Trends in incidence, prevalence, and survival of primary liver cancer in the United Kingdom (2000-2021).

  英国で肝がん罹患増加、生存率は依然低い状況が続く課題多く残る

  対象DB：CPRD

  35. Mind the Gaps: Literature Survey Reveals Shortcomings in Handling Missing Data in Clinical Practice Research Datalink (CPRD), a UK Primary Care Health Records Database.

  英国EHR研究で欠測処理が不適切と判明

  対象DB：CPRD

  36. The Identification of Potential Treatment Targets to Reduce the Risk of Obesity-Related Complications: A Step Toward a Treat-to-Target Approach in Obesity Management.

  BMI27・WHtR0.53が肥満治療目標指標

  対象DB：CPRD

  37. Sodium glucose co-transporter 2 inhibitors versus dipeptidyl peptidase-4 inhibitors and the risk of ventricular arrhythmia among patients with type 2 diabetes: A population-based cohort study.

  SGLT2阻害薬は心室不整脈リスクと無関連

  対象DB：CPRD

  38. Understanding the role of COVID-19 vaccination in all-cause healthcare resource utilisation among adults with long covid in the Uk primary care setting: data from the 2022-2023 respiratory virus season.

  ワクチンは長期COVIDに影響少なく受診減少

  対象DB：THIN

  39. Sugammadex hypersensitivity: a national retrospective cohort study from the French pharmacovigilance database.

  スガマデクス過敏症を全国で後方視解析した研究

  対象DB：FPVD

  40. Changes in psychotropic medication prescription patterns during the COVID-19 pandemic among Japanese children, adolescents and young adults: interrupted time-series study using a national claims database.

  若年層でコロナ後に向精神薬処方が増加した

  対象DB：DeSC

  41. Myelodysplastic Syndromes and Incident Cardiovascular Disease: A Nationwide, Real-World Cohort Study.

  MDSは心血管疾患リスクを独立して増加させる

  対象DB：DeSC

  42. Percutaneous ventricular assist devices for percutaneous coronary interventions in older patients with heart failure: a target trial emulation.

  高齢HF患者のPCIでpVADとIABPの予後に差なし

  対象DB：DeSC

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