論文・技術情報追加のお知らせ

1. Disproportionality analysis of taste disorders using the FDA adverse event reporting system and Japanese adverse drug event report databases.

薬剤性味覚障害、FAERS/JADERで関連薬を網羅的同定

対象DB：JADER

2. Association between opioid analgesics and learning disorders: a disproportionality analysis of the FDA adverse event reporting system (FAERS) and EudraVigilance databases.

オピオイド、胎児期曝露で学習障害報告が多い

対象DB：EudraVigilance

3. Post-marketing surveillance of upadacitinib: multilevel analysis of venous thromboembolism reporting in global data and rheumatoid arthritis.

ウパダシチニブは他JAK阻害薬比でVTEリスク増加は示されなかった

対象DB：VigiBase

4. Guillain-Barre syndrome associated with immune checkpoint inhibitors exposure: a pharmacovigilance study.

免疫チェックポイント阻害薬とGBS発症の関連をVigiBaseで確認

対象DB：VigiBase

5. Analysis of anticancer drug associated adverse reactions in depressive patients from vigibase.

VigiBaseで抑うつ患者の抗がん薬副作用を解析

対象DB：VigiBase

6. Effectiveness and safety of prasugrel- versus clopidogrel-based dual antiplatelet therapy for acute ischemic stroke.

急性アテロ血栓性脳卒中でプラスグレルDAPTは有効性向上も出血増

対象DB：DPC

7. Association between embolic agent choice and complications after transcatheter arterial embolization for colonic diverticular bleeding.

結腸憩室出血TAEでは塞栓物質で再出血・虚血リスクが異なる

対象DB：DPC

8. Age-related epidemiology and outcomes of sepsis in Japanese critical care units: a nationwide administrative claims database study.

超高齢者敗血症は治療強度低下と高死亡率が顕著

対象DB：DPC

9. Postpartum haemorrhage in pregnant carriers of haemophilia and women with von Willebrand disease: a nationwide inpatient database study.

血友病保因者の産後出血は増加せず、VWDではリスク上昇

対象DB：DPC

10. Trends and factors associated with potentially inappropriate medication use in older adults hospitalized for heart failure: A nationwide analysis using the JROAD-DPC database.

心不全悪化薬は減少も依然多用、女性で高頻度―全国DPC解析

対象DB：DPC

11. Global burden of lower respiratory infections and aetiologies, 1990-2023: a systematic analysis for the Global Burden of Disease Study 2023.

下気道感染は依然高負荷、乳幼児減少も高齢者で深刻

対象DB：KAERS,VAERS

12. MMRV vaccine safety: A comprehensive analysis of adverse events recorded among pediatric populations.

MMRV安全性解析、喘息・てんかん児で早期有害事象に注意

対象DB：VAERS

13. Trends in the incidence of hip fractures and osteoporosis treatment in Japan (FY2012-FY2023).

コロナ禍で骨粗鬆症治療率低下し大腿骨骨折が再増加

対象DB：NDB

14. Clinical significance of imeglimin in older patients with type 2 diabetes: Analysis of a national database and a long-term case suggesting the potential for sarcopenia prevention.

高齢2型糖尿病でイメグリミンが血糖安定と治療継続に寄与

対象DB：NDB

15. Risk assessment of daikenchuto-induced hepatobiliary injury in colon cancer patients post-colectomy: a retrospective cohort study.

大建中湯は結腸切除後の肝胆道障害リスクを増加させなかった

対象DB：MDV

16. Initial treatment of COPD with LABA-ICS or LABA-LAMA: real-world comparative effectiveness.

COPD初期治療、増悪多発例ではLABA-ICSが有効

対象DB：CPRD

17. Acute effects of daylight saving time clock changes on mental and physical health in England: population based retrospective cohort study.

秋の時刻変更後、心身イベントが一時的に減少

対象DB：CPRD

18. Frailty, diabetic foot ulceration and mortality in people diagnosed with type 2 diabetes: Multistate analysis of primary care patients in the UK clinical practice research datalink.

2型糖尿病で虚弱は足潰瘍・死亡リスク増大

対象DB：CPRD

19. The association between multiple long-term conditions and dementia: A UK cohort study.

多疾患併存は認知症リスクを大幅に高める

対象DB：CPRD

20. Comparison of Epidemiological Estimates for 19 Cancer Types Using Electronic Health Record Databases in England: An Analysis of CPRD Aurum and CPRD GOLD Databases with Linked Hospital Episode Statistics and Cancer Registry Data.

CPRD癌研究は目的別に連結データ活用が重要

対象DB：CPRD

21. Burden of long-term conditions and management of people with overweight and obesity: Data from the United Kingdom primary care cohort of the IMPACT-O study.

英国肥満患者は併存症が多く治療介入は限定的

対象DB：THIN

22. Evaluating seizures associated with novel antineoplastic agents during breast cancer treatment using the Food and Drug Administration Adverse Event Reporting System and Canada Vigilance Adverse Reaction Online Database.

乳癌新規治療薬でけいれん報告増加を確認

対象DB：CVAR

23. Survey on the Actual Use of Topical Anti-Inflammatory Drugs Among Patients with Atopic Dermatitis.

アトピー寛解期の外用薬指導は不十分で実践に差

対象DB：DeSC

24. Persistence of romosozumab vs. teriparatide in Japanese older adults aged >/= 75 years with osteoporosis: a population-based cohort study.

高齢骨粗鬆症患者でロモソズマブは継続率が高い

対象DB：DeSC

25. Uptake, Geographic Access, and Outcomes of Transcatheter Mitral Valve Repair in the United States.

M-TEER施設拡大と症例数が短期・長期予後に与える影響

対象DB：DeSC