論文・技術情報追加のお知らせ

1. Integrated pharmacovigilance assessment of drug-associated cholangitis: signal detection, clinical characterization, and mechanistic insights.

薬剤性胆管炎の不均衡分析と時間発現プロファイルの評価。

対象DB：FAERS

2. Comparative Risk of Hyponatremia Among Patients Treated With Second-Generation Antipsychotics.

第二世代抗精神病薬における低ナトリウム血症リスクの比較。

対象DB：FAERS,MDV

3. Disproportionality analysis of atrial fibrillation associated with direct oral anticoagulants: A pharmacovigilance study using the Food and Drug Administration adverse event reporting system database.

直接経口抗凝固薬関連の心房細動における不均衡分析調査。

対象DB：FAERS

4. Investigation of Adverse Events Associated with Predicted GnRHR Agonists Using the FAERS Database.

機械学習によるGnRHR作動薬予測とFAERS副作用シグナル解析。

対象DB：FAERS

5. Disproportionality analysis of adverse events associated with tyrosine kinase inhibitors in gastrointestinal stromal tumors in the FDA adverse event reporting system.

GIST治療におけるTKIの副作用プロファイルに関する比較解析。

対象DB：FAERS

6. Comprehensive analysis of etrasimod-related adverse events based on the FDA Adverse Event Reporting System database.

エトラシモド関連有害事象のFAERSに基づく総合解析。

対象DB：FAERS

7. Gastrointestinal adverse events related to monoclonal antibodies: A comprehensive evaluation of data from the FDA Adverse Event Reporting System database.

各種モノクローナル抗体による消化器系有害事象の不均衡分析。

対象DB：FAERS

8. Perioperative Nursing Management of Unintended Retained Foreign Object-Related Events in Neurosurgery: Insights From a 16-Year Study in China.

術中異物残留関連有害事象の周術期看護管理に関する実態調査。

対象DB：FAERS

9. Safety signals for drug-related respiratory depression: a disproportionality analysis of the FDA Adverse Event Reporting System (FAERS).

FAERSを用いた薬剤性呼吸抑制シグナルの不均衡分析調査。

対象DB：FAERS

10. Ocular adverse events associated with immune checkpoint inhibitors: a pharmacovigilance analysis of the FAERS database.

免疫チェックポイント阻害薬に伴う眼有害事象の不均衡分析。

対象DB：FAERS

11. Real-world analysis of depression-related adverse events associated with the adsorbed anthrax vaccine: integrating pharmacovigilance signals, machine learning risk prediction, and transcriptomic mechanisms.

FAERSを用いた吸着沈殿炭疽ワクチンのうつ関連有害事象の解析。

対象DB：FAERS,VAERS

12. Adverse Drug Events Associated With Six Classes of Glaucoma Medications: A Retrospective Pharmacovigilance Study Using Real-World Data From The FAERS Database.

緑内障治療薬6系統における有害事象の比較リスク分析調査。

対象DB：FAERS

13. Antibiotic-associated adverse events in bone and joint infections: a FAERS pharmacovigilance study.

骨関節感染症における長期抗菌薬投与に伴う副作用シグナル評価。

対象DB：FAERS

14. Adverse events of cetuximab sarotalocan in photoimmunotherapy: insights from the Japanese adverse drug event report database.

セツキシマブサロタロカンにおける副作用のFAERS解析。

対象DB：JADER

15. Digoxin Dosing Errors, Drug Interactions and Off-Label Risks: Insights from an EudraVigilance Disproportionality Analysis.

ジゴキシン誤投与・薬物相互作用・適応外使用リスクの実態調査。

対象DB：EudraVigilance

16. Comparative potential for generating spontaneous signals for abuse and dependence among drugs used for attention deficit hyperactivity disorder: A disproportionality analysis in VigiBase(R).

ADHD治療薬における乱用・依存の自発報告シグナル比較調査。

対象DB：VigiBase

17. Etiology of pericardial effusion requiring invasive drainage: nationwide study in Japan.

侵襲的ドレナージを要する心嚢液貯留の病因に関する全国調査。

対象DB：DPC

18. Nationwide Practice Patterns of Early Postoperative Kampo Medicine after Gastrectomy for Gastric Cancer: A Japanese Administrative Database Study.

胃切除術後の早期漢方薬投与に関する日本全国の実態パターン解析。

対象DB：DPC

19. Impact of cognitive impairment on postoperative delirium and discharge disposition following knee arthroplasty: a Japanese nationwide propensity score-matched study.

膝関節全置換術後の認知機能障害がせん妄や退院先に与える影響。

対象DB：DPC

20. Impact of a national reimbursement policy for secondary fracture prevention on early secondary fractures after hip fracture surgery in Japan: a nationwide interrupted time series analysis.

大腿骨近位部骨折後の二次性骨折予防に関する診療報酬改定の評価。

対象DB：DPC

21. Fracture laterality as an independent prognostic factor for clinical outcomes after hip fracture surgery : an analysis of 72,008 patients.

大腿骨近位部骨折手術後の転帰における骨折側性の予後因子解析。

対象DB：DPC

22. Association of implementation of secondary fracture prevention incentives after hip fracture and risk of subsequent fracture in real-world practice.

大腿骨近位部骨折後の二次性骨折予防インセンティブの導入効果。

対象DB：DPC

23. Association between ambient temperature and all-cause hospitalization by functional status in Japan: A time-stratified case-crossover study.

身体機能障害の有無による外気温と全因入院リスクの関連性解析。

対象DB：DPC

24. Association Between Registered Instructors of Cardiac Rehabilitation and Inpatient Cardiac Rehabilitation Participation in Japan: A Nationwide 10-Year Analysis.

心不全患者における心臓リハ指導士配置と死亡率の関連調査。

対象DB：DPC

25. Regional variations in diabetes prevalence and their associations with obesity and dietary habits: An ecological cross-sectional study using the National Database of Japan.

アジアにおける糖尿病肥満非肥満フェノタイプの地域差と関連要因。

対象DB：NDB

26. Early implementation of radiofrequency ablation for breast cancer in Japan: What national claims data reveal and obscure.

早期乳がんに対するラジオ波焼灼療法の早期導入における実態調査。

対象DB：NDB

27. Diverging Trends in Home Respiratory Care in an Aging Society: National Data from Japan.

超高齢社会における在宅呼吸療法（HOT・HMV）の動向分析。

対象DB：NDB

28. Changes in Oral Analgesic Prescribing in Japan between Fiscal Year 2014 and Fiscal Year 2022: A Nationwide Analysis Using Open Data from the National Database of Health Insurance Claims and Specific Health Checkups of Japan.

日本における経口鎮痛薬処方パターンの経時的変化に関する調査。

対象DB：NDB

29. Major cardiovascular events in Japanese patients with acute and chronic coronary syndrome.

急性および慢性冠症候群患者における主要心血管イベントの発生率。

対象DB：MDV

30. Characterising intra-articular corticosteroid injections use in UK primary care: a retrospective cohort study between 2005 and 2020.

英国プライマリケアにおける関節内ステロイド注射の使用実態調査。

対象DB：CPRD

31. Exploring the risk of venous thromboembolism in women with rheumatoid arthritis initiating menopausal hormone treatment in England.

関節リウマチ女性の更年期ホルモン療法と血栓症リスクの解析。

対象DB：CPRD

32. Weight status and pathways to eating disorder referral from primary care in England and Northern Ireland: a cross-sectional analysis of routine care data.

英国プライマリケアにおける体重状態と摂食障害受診経路の解析。

対象DB：CPRD

33. Antidepressant Use During Pregnancy and Birth Outcomes: Analysis From the UK, Norway, and Sweden.

妊娠中の抗うつ薬使用と出生転帰の関連性に関する多国籍コホート。

対象DB：CPRD

34. Impact of adjunctive dihydropyridine calcium channel blockers on mental health outcomes in people with severe mental illness: A target trial emulation in English electronic health records.

高血圧患者におけるDHP系CCB追加の精神症状への影響の評価。

対象DB：CPRD

35. Examining variations in adherence to guideline-recommended post-acute kidney injury care in primary care in England: a population-based cohort study.

急性腎障害後のガイドライン推奨ケア遵守における地域・施設間差異。

対象DB：CPRD

36. Diagnostic and prognostic outcomes for men with prostate cancer detected through opportunistic, asymptomatic PSA testing or symptomatic presentation to primary care: The PC3 cohort study.

英国におけるPSA検査経由で発見された前立腺がんの転帰評価。

対象DB：CPRD

37. Effectiveness of beta-blockers in COPD and CVD: Real-world effects on mortality.

COPD併存心血管疾患患者におけるβ遮断薬の死亡率抑制効果。

対象DB：CPRD

38. Incidence and risk factors for postoperative myocardial infarction following hip and knee arthroplasty.

人工股関節・膝関節置換術後の術後心筋梗塞の発症率とリスク因子。

対象DB：CPRD

39. Clinical Reality and Outcomes of Home Semi-Solid Enteral Nutrition Guidance and Management Using a Medical Claims Database in Japan: A Retrospective Cohort Study.

在宅半固形経管栄養指導および実施に関する臨床実態と転帰調査。

対象DB：DeSC

40. Heterogeneous Treatment Effects of Renal Replacement Therapy in Critically Ill Patients: A Multicenter Observational Study Using a Japanese ICU Registry.

重症急性腎障害患者における腎代替療法の導入時期に関する研究。

対象DB：DeSC

41. Bowel Obstruction/Ileus Associated With the Use of Glucagon-Like Peptide-1 Receptor Agonists: A Nationwide Database Study.

GLP-1受容体作動薬と腸閉塞・イレウス発症リスクの関連性評価。

対象DB：DeSC