| アブストラクト | BACKGROUND: Women with overweight (a body mass index of >/= 25 kg/m(2)) or obesity (a body mass index of >/= 30 kg/m(2)) are at greater risk of experiencing complications during pregnancy and labour than women with a healthy weight. Women who remove their long-acting reversible contraception (i.e. coils or implants) are one of the few groups of people who contact services as part of their preparation for conception, creating an opportunity to offer a weight loss intervention. OBJECTIVES: The objectives were to understand if routine NHS data captured the pathway from long-acting reversible contraception removal to pregnancy and included body mass index; to identify the suitable components of a preconception weight loss intervention; and to engage with key stakeholders to determine the acceptability and feasibility of asking women with overweight/obesity to delay the removal of their long-acting reversible contraception in order to take part in a preconception weight loss intervention. DESIGN: This was a preparatory mixed-methods study, assessing the acceptability and feasibility of a potential intervention, using routine NHS data and purposefully collected qualitative data. PARTICIPANTS: The NHS routine data included all women with a long-acting reversible contraception code. There were three groups of participants in the surveys and interviews: health-care practitioners who remove long-acting reversible contraception; weight management consultants; and women of reproductive age with experience of overweight/obesity and of using long-acting reversible contraception. SETTING: UK-based health-care practitioners recruited at professional meetings; and weight management consultants and contraceptive users recruited via social media. DATA SOURCES: Anonymised routine data from UK sexual health clinics and the Clinical Practice Research Datalink, including the Pregnancy Register; and online surveys and qualitative interviews with stakeholders. RESULTS: The records of 2,632,871 women aged 16-48 years showed that 318,040 had at least one long-acting reversible contraception event, with 62% of records including a body mass index. Given the identified limitations of the routine NHS data sets, it would not be feasible to reliably identify women with overweight/obesity who request a long-acting reversible contraception removal with an intention to become pregnant. Online surveys were completed by 100 health-care practitioners, four weight management consultants and 243 contraceptive users. Ten health-care practitioners and 20 long-acting reversible contraception users completed qualitative interviews. A realist-informed approach generated a hypothesised programme theory. The combination of weight discussions and the delay of long-acting reversible contraception removal was unacceptable as an intervention to contraceptive users for ethical and practical reasons. However, a preconception health intervention incorporating weight loss could be acceptable, and one potential programme is outlined. LIMITATIONS: There was very limited engagement with weight management consultants, and the sample of participating stakeholders may not be representative. CONCLUSIONS: An intervention that asks women to delay long-acting reversible contraception removal to participate in a preconception weight loss intervention would be neither feasible nor acceptable. A preconception health programme, including weight management, would be welcomed but requires risk communication training of health-care practitioners. FUTURE WORK: Work to improve routine data sets, increase awareness of the importance of preconception health and overcome health-care practitioner barriers to discussing weight as part of preconception care is a priority. TRIAL REGISTRATION: This trial is registered as ISRCTN14733020. FUNDING: This project was funded by the National Institute for Health and Care Research (NIHR) Health Technology Assessment programme and will be published in full in Health Technology Assessment; Vol. 27, No. 1. |
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| ジャーナル名 | Health technology assessment (Winchester, England) |
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| 投稿日 | 2023/1/24 |
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| 投稿者 | Channon, Susan; Coulman, Elinor; Cannings-John, Rebecca; Henley, Josie; Lau, Mandy; Lugg-Widger, Fiona; Strange, Heather; Davies, Freya; Sanders, Julia; Scherf, Caroline; Couzens, Zoe; Morantz, Leah |
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| 組織名 | Centre for Trials Research, Cardiff University, Cardiff, UK.;The Welsh Centre for Primary and Emergency Care Research (PRIME), Division of;Population Medicine, Cardiff University, Cardiff, UK.;School of Healthcare Sciences, College of Biomedical and Life Sciences, Cardiff;University, Cardiff, UK.;Cardiff and Vale University Health Board, Department of Sexual Health, Cardiff;Royal Infirmary, Cardiff, UK.;Public Health Wales NHS Trust, Public Health Wales, Cardiff, UK. |
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| Pubmed リンク | https://www.ncbi.nlm.nih.gov/pubmed/36688498/ |
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