アブストラクト | BACKGROUND: Kawasaki disease (KD) induces coronary arteritis, which causes subsequent coronary aneurysms, and contributes to acute myocardial infarction (AMI). However, the differences regarding real-world treatment selection and mortality between AMI-complicated KD and AMI due to typical atherosclerosis (AMI-non KD) are unknown. AIM: The aim of the present study was to examine the current treatment strategy and prognosis of AMI-complicated KD compared with AMI due to typical atherosclerosis. METHOD: We used data from 2012 to 2019 from a nationwide claim database, the Japanese Registry of All Cardiac and Vascular Diseases-Diagnosis Procedure Combination. RESULTS: Compared to the AMI-non KD patients (n = 70,227), the AMI-complicated KD patients (n = 73): (1) underwent percutaneous coronary intervention (PCI) less often and more coronary artery bypass grafting, intracoronary thrombolysis or intravenous coronary thrombolysis more often; (2) underwent stentless PCI using old balloon angioplasty or rotablator, when they underwent PCI; and (3) needed in-hospital cardiopulmonary resuscitation and intensive mechanical therapy such as intra-aortic balloon pump, percutaneous cardiopulmonary support or a respirator. Both the AMI-non KD and AMI-complicated KD patients had similar in-hospital mortality rates. CONCLUSIONS: Compared with AMI-non KD patients, AMI-complicated KD patients underwent non-PCI strategies such as bypass surgery or thrombolysis, and required intensive therapy with mechanical supports more often, but presented similar in-hospital mortality. When the AMI-complicated KD patients underwent PCI, stentless PCI using balloon angioplasty or rotablator was performed more often compared with the AMI-non KD patients. |
ジャーナル名 | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions |
Pubmed追加日 | 2022/11/2 |
投稿者 | Anzai, Fumiya; Yoshihisa, Akiomi; Takeishi, Ryohei; Hotsuki, Yu; Sato, Yu; Sumita, Yoko; Nakai, Michikazu; Misaka, Tomofumi; Takeishi, Yasuchika |
組織名 | Department of Cardiovascular Medicine, Fukushima Medical University, Fukushima,;Japan.;Department of Clinical Laboratory Sciences, Fukushima Medical University School;of Health Science, Fukushima, Japan.;Department of Medical and Health Information Management, National Cerebral and;Cardiovascular Center, Suita, Japan. |
Pubmed リンク | https://www.ncbi.nlm.nih.gov/pubmed/36316815/ |