| アブストラクト | Aim: Biliary tract cancers are aggressive, with poor prognosis. This study describes clinical characteristics, treatment patterns and healthcare resource utilization in patients with metastatic biliary tract cancer in Japan. Materials & methods: This cohort-based study collected data from the Japan Medical Data Center claims database (2014-2018). Results: A total of 325 patients were included; 65.2% were male and the mean age was 59.2 years. A 47.6% had an Elixhauser Comorbidity Index score >/=5. Most frequent regimens were gemcitabine + cisplatin (52.9%) for first-line therapy and tegafur + gimeracil + oteracil for second-line therapy (48.6%) and third-line therapy (27.2%). Approximately 77% of patients had >/=1 hospital admission, with a median length of 57 days. Conclusion: This study provides insights on the characteristics and burden of metastatic biliary tract cancer in Japan, highlighting high disease burden in a younger population. |
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| ジャーナル名 | Journal of comparative effectiveness research |
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| 投稿日 | 2023/5/31 |
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| 投稿者 | Argoubi, Ramzi; Reese, Emily S; Furegato, Martina; Medina, Patricia; Bobiak, Sarah |
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| 組織名 | Cerner Enviza, Kansas City, MO 64117, USA.;EMD Serono Research & Development Institute, Inc, Billerica, MA 01821, USA, an;affiliate of Merck KGaA. |
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| Pubmed リンク | https://www.ncbi.nlm.nih.gov/pubmed/37256267/ |
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