| アブストラクト | PURPOSE: To examine the associations between premorbid nutritional status and in-hospital mortality in severe burn patients according to age in Japan. METHODS: We retrospectively extracted the data of 14,345 patients aged 18-84 years admitted for burns from April 1, 2014, to March 31, 2018, using the Japanese Diagnosis Procedure Combination database. The exclusion criteria were out-of-hospital cardiac arrest, death in the emergency room, readmission, and planned admission. We collected data on age, sex, height, weight, comorbidities, burn index, and mechanical ventilation use and performed age-stratified multilevel logistic regression analyses to estimate associations between premorbid body mass index (BMI) and in-hospital mortality. RESULTS: We analyzed 2968 patients with a burn index >/=10, including 831 elderly aged 75-84 years. In patients aged 18-74 years, being underweight (BMI < 18.5) significantly decreased mortality (0.34 [0.15-0.77]; P = 0.010). In contrast, in patients aged 75-84 years, being underweight significantly increased mortality (2.11 [1.05-4.25]; P = 0.036). Being overweight (BMI >25) increased mortality in both age groups, but not significantly. CONCLUSIONS: The results suggest that pre-morbidly underweight elderly patients aged 75-84 years with severe burns have high mortality risks. Further research is needed to identify optimal care strategies for this population. |
|---|
| 組織名 | Department of Intensive Care Medicine, University Hospital of Occupational and;Environmental Health, Japan, 1-1 Iseigaoka, Yahatanishi-ku, Kitakyushu, Fukuoka;807-8556, Japan. Electronic address: stargazer.m27@gmail.com.;Department of Preventive Medicine and Community Health, School of Medicine,;University of Occupational and Environmental Health, Japan, 1-1 Iseigaoka,;Yahatanishi-ku, Kitakyushu, Fukuoka 807-8555, Japan. Electronic address:;km@med.uoeh-u.ac.jp.;Yahatanishi-ku, Kitakyushu, Fukuoka 807-8555, Japan; Occupational Health Data;Science Center, University of Occupational and Environmental Health, Japan, 1-1;Iseigaoka, Yahatanishi-ku, Kitakyushu, Fukuoka 807-8555, Japan. Electronic;address: smatsuda@med.uoeh-u.ac.jp.;Department of Health Policy and Informatics, Tokyo Medical and Dental University;Graduate School, 1-5-45 Yushima, Bunkyo-ku, Tokyo 113-8519, Japan. Electronic;address: kfushimi.hci@tmd.ac.jp.;Department of Emergency and ICU, Steel Memorial Yawata Hospital, 1-1-1;Harunomachi, Yahatahigashi-ku, Kitakyushu, Fukuoka 805-8508, Japan. Electronic;address: kaizuka@alles.or.jp.;807-8556, Japan. Electronic address: kamochi@clnc.uoeh-u.ac.jp. |
|---|
