| アブストラクト | This study aimed to clarify the relationship between carbapenem consumption and clinical outcome using the diagnosis procedure combination (DPC) payment system database (2020) published by the Ministry of Health, Labour, and Welfare of Japan. This study divided 5316 medical facilities subject to aggregation into five facilities and calculated the median values, including facility characteristics, clinical outcomes, and carbapenem consumption. Next, a correlation analysis was performed between carbapenem consumption and clinical outcome, as well as a multiple regression analysis between carbapenem consumption as the dependent variable and clinical outcome, bed size, and proportion of patients by disease as independent variables. Additionally, three clinical outcomes available from the DPC payment system database were selected, including cure, readmission within 4 weeks, and the average length of stay. This study revealed no relationship between carbapenem consumption and clinical outcome in university hospitals and university hospital-equivalent community hospitals; however, a relationship was suggested in the community, DPC-prepared, and non-DPC hospitals. University hospitals and university hospital-equivalent community hospitals with a high consumption of carbapenems may need to reconsider the classification because of the limited number of facilities in this classification. |
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| ジャーナル名 | Antibiotics (Basel, Switzerland) |
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| 投稿日 | 2022/12/24 |
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| 投稿者 | Yamaguchi, Kozue; Maeda, Masayuki; Ohmagari, Norio; Muraki, Yuichi |
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| 組織名 | Division of Infection Control Sciences, Department of Clinical Pharmacy, School;of Pharmacy, Showa University, Tokyo 142-8555, Japan.;AMR Clinical Reference Center, Disease Control and Prevention Center, National;Center for Global Health and Medicine, Tokyo 162-8655, Japan.;Department of Clinical Pharmacoepidemiology, Kyoto Pharmaceutical University,;Kyoto 607-8414, Japan. |
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| Pubmed リンク | https://www.ncbi.nlm.nih.gov/pubmed/36551464/ |
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