| アブストラクト | OBJECTIVE: This study aimed to detect cardiovascular disease-related signals using Global Individual Case Safety Report data on JAK inhibitors. MATERIALS AND METHODS: A signal detection study was conducted using the WHO-UMC VigiBase. RESULTS: This study identified four cardiovascular adverse event signals associated with JAK inhibitors in Asian populations, including pulmonary embolism, deep vein thrombosis, thrombosis, and cerebrovascular accidents. CONCLUSION: Analysis of Asian populations revealed a higher risk of thromboembolic events associated with JAK inhibitors than with TNF inhibitors. However, unlike in the Western populations, no myocardial infarction signal was detected in the Asian populations. |
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| ジャーナル名 | International journal of clinical pharmacology and therapeutics |
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| Pubmed追加日 | 2025/2/27 |
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| 投稿者 | Nam, Woongshik; Bae, Ji-Hwan; Oh, Jeongin; Shin, Ju-Young; Kim, Hoon |
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| 組織名 | |
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| Pubmed リンク | https://www.ncbi.nlm.nih.gov/pubmed/40013961/ |
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