| アブストラクト | BACKGROUND: Few studies have investigated the effect of the COVID-19 pandemic on mental health beyond 2020. This study quantifies changes to healthcare utilisation and symptoms for common mental health problems over the pandemic's first 21 months. METHODS: Parallel cohort studies using primary care database and survey data for adults (>/=16 years) in England from January 2015 to December 2021: 16,551,842 from the Clinical Practice Research Datalink (CPRD) and 40,699 from the UK Household Longitudinal Survey (UKHLS). Interrupted time-series models estimated changes in monthly prevalence of presentations and prescribed medications for anxiety and depression (CPRD); and self-reported psychological distress (UKHLS). The pandemic period was divided into five phases: 1st Wave (April-May 2020); post-1st Wave (June-September 2020); 2nd Wave (October 2020-February 2021); post 2nd Wave (March-May 2021); 3rd Wave (June-December 2021). FINDINGS: Primary care presentations for depression or anxiety dropped during the first wave (4.6 fewer monthly appointments per 1000 patients, 4.4-4.8) and remained lower than expected throughout follow-up. Self-reported psychological distress exceeded expected levels during the first (Prevalence Ratio = 1.378, 95% CI 1.289-1.459) and second waves (PR = 1.285, 1.189-1.377), returning towards expected levels during the third wave (PR = 1.038, 0.929-1.154). Increases in psychological distress and declines in presentations were greater for women. The decrease in primary care presentations for depression and anxiety exceeded that for physical health conditions (rheumatoid arthritis, diabetes, urinary tract infections). Anxiety and depression prescriptions returned to pre-pandemic levels during the second wave due to increased repeat prescriptions. INTERPRETATION: Despite periods of distress during the pandemic, we did not find an enduring effect on common mental health problems. The fall in primary care presentations for anxiety or depression suggests changing healthcare utilisation for mental distress and a potential treatment gap. FUNDING: National Institute for Health and Care Research (NIHR). |
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| 投稿者 | Taxiarchi, Vicky P; Senior, Morwenna; Ashcroft, Darren M; Carr, Matthew J; Hope, Holly; Hotopf, Matthew; Kontopantelis, Evangelos; McManus, Sally; Patalay, Praveetha; Steeg, Sarah; Webb, Roger T; Abel, Kathryn M; Pierce, Matthias |
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| 組織名 | Faculty of Biology, Medicine and Health, Division of Psychology and Mental;Health, Centre for Women's Mental Health, University of Manchester, Manchester,;UK.;Faculty of Biology, Medicine and Health, Division of Pharmacy and Optometry, The;University of Manchester, Manchester, UK.;National Institute for Health and Care Research (NIHR) Greater Manchester Patient;Safety Research Collaboration (GM PSRC), University of Manchester, UK.;Department of Psychological Medicine, Institute of Psychiatry Psychology and;Neuroscience, King's College London, London, UK.;Faculty of Biology, Medicine and Health, Division of Informatics, Imaging and;Data Sciences, The University of Manchester, Manchester, UK.;Violence and Society Centre, City, University of London, London EC1V 0HB, UK.;Centre for Longitudinal Studies and MRC Unit for Lifelong Health and Ageing,;University College London, London, UK.;Division of Psychology & Mental Health, Centre for Mental Health and Safety, The;NIHR School for Primary Care Research, UK. |
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