| アブストラクト | Acute generalised exanthematous pustulosis (AGEP) is a rare but serious cutaneous adverse drug reaction, often related to antibiotics such as beta-lactams or macrolides. However, it is rarely associated with clindamycin which belongs to the lincosamide antibiotics. The Netherlands Pharmacovigilance Centre Lareb received five reports of AGEP associated with the use of clindamycin. We present these five cases and provide support for this association from the Lareb database, the database of the WHO Collaborating Centre for International Drug Monitoring (Vigibase), the database of the European Medicine Agency (Eudravigilance), and from a mini review of the literature. |
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| ジャーナル名 | The Netherlands journal of medicine |
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| Pubmed追加日 | 2016/12/15 |
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| 投稿者 | Smeets, T J L; Jessurun, N; Harmark, L; Kardaun, S H |
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| 組織名 | 1Netherlands Pharmacovigilance Centre Lareb, 's-Hertogenbosch, the Netherlands. |
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| Pubmed リンク | https://www.ncbi.nlm.nih.gov/pubmed/27966434/ |
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