| アブストラクト | Shoshin beriberi is a fulminant form of wet beriberi, but there are no large-scale studies detailing the clinical features of this disease. We investigated the clinical features and outcomes of Shoshin beriberi using data from a nationwide database in Japan.Using the Diagnosis Procedure Combination database, we identified patients with Shoshin beriberi between July 2010 and March 2021. We retrospectively investigated the characteristics, comorbidities, treatment, and in-hospital mortality of patients with Shoshin beriberi. The chi-square test or Fisher's exact test was used for categorical variables, and the Mann-Whitney U-test was used for continuous variables.We identified 62 patients with Shoshin beriberi. The median (interquartile range) age was 63 (48-69) years. Furthermore, 54 patients were male (87%). The most common comorbidity was alcohol-related disorder (34%). The median (interquartile range) length of hospital and intensive care unit stays were 17 (range, 10-35) and 5 (range, 1-9) days, respectively. The proportion of patients who received venoarterial extracorporeal membrane oxygenation, intra-aortic balloon pump, continuous renal replacement therapy, and mechanical ventilation was 11, 5, 29, and 63%, respectively. Among the patients with Shoshin beriberi, 53% received 2 or more catecholamines or inotropes. The in-hospital mortality was 23%. Impaired consciousness at admission was significantly related to in-hospital death (P < 0.001).The present study is the first and largest to describe the clinical features of patients with Shoshin beriberi using a nationwide database. Impaired consciousness at admission was significantly associated with in-hospital death. |
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| ジャーナル名 | International heart journal |
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| 投稿日 | 2024/3/14 |
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| 投稿者 | Mizuguchi, Yoshiki; Mouri, Hideyuki; Jo, Taisuke; Hashimoto, Yohei; Matsui, Hiroki; Fushimi, Kiyohide; Yasunaga, Hideo; Taniguchi, Takumi |
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| 組織名 | Department of Anesthesiology and Intensive Care Medicine, Kanazawa University.;Department of Health Services Research, Graduate School of Medicine, The;University of Tokyo.;Department of Respiratory Medicine, The University of Tokyo Hospital.;Save Sight Institute, The University of Sydney, South Block, Sydney Eye Hospital.;Department of Clinical Epidemiology and Health Economics, School of Public;Health, The University of Tokyo.;Department of Health Policy and Informatics, Tokyo Medical and Dental University;Graduate School of Medicine and Dental Science. |
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| Pubmed リンク | https://www.ncbi.nlm.nih.gov/pubmed/38479848/ |
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