| アブストラクト | Venoarterial extracorporeal membrane oxygenation (VA-ECMO) has been widely used for critically ill patients all over the world; however, comprehensive survey regarding the relationship between VA-ECMO duration and prognosis is limited. We conducted a survey of VA-ECMO patients in the Japanese Registry of All Cardiac and Vascular Diseases-Diagnosis Procedure Combination (JROAD-DPC), which was a health insurance claim database study among cardiovascular centers associated with the Japan Circulation Society, between April 2012 and March 2016. Out of 13,542 VA-ECMO patients, we analyzed 5766 cardiovascular patients treated with VA-ECMO. 68% patients used VA-ECMO only for 1 day and 93% had VA-ECMO terminated within 1 week. In multivariate analysis, the hazard ratio of 1-day support was significantly high at 1.72 (95% confidence intervals; 95% CI 1.53-1.95) (p < 0.001), while that of 2-day [0.60 (95% CI 0.49-0.73)], 3-day [0.75 (95% CI 0.60-0.94)], 4-day [0.43 (95% CI 0.31-0.60)] and 5-day support [0.62 (95% CI 0.44-0.86)] was significantly low. Comprehensive database analysis of JROAD-DPC revealed that cardiovascular patients who were supported with VA-ECMO for 2-5 days showed lower mortality. The optimal VA-ECMO support window should be investigated in further studies. |
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| ジャーナル名 | Heart and vessels |
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| 投稿日 | 2022/9/30 |
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| 投稿者 | Sakamoto, Kazuo; Matoba, Tetsuya; Nakai, Michikazu; Tahara, Yoshio; Nakashima, Takahiro; Hosoda, Hayato; Miyamoto, Yoshihiro; Nishimura, Kunihiro; Sumita, Yoko; Yagi, Tsukasa; Ichimura, Kenzo; Yonemoto, Naohiro; Tachibana, Eizo; Nagao, Ken; Ikeda, Takanori; Sato, Naoki; Tsutsui, Hiroyuki |
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| 組織名 | Department of Cardiovascular Medicine, Kyushu University Hospital, 3-1-1;Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan.;matoba@cardiol.med.kyushu-u.ac.jp.;Department of Statistics and Data Analysis, Center for Cerebral and;Cardiovascular Disease Information, National Cerebral and Cardiovascular Center,;Osaka, Japan.;Department of Cardiovascular Medicine, National Cerebral and Cardiovascular;Center, Osaka, Japan.;Preventive Medicine and Epidemiology Informatics, Center for Cerebral and;Department of Cardiology, Kawaguchi Municipal Medical Center, Kawaguchi, Japan.;Department of Biostatistics, Kyoto University School of Public Health, Kyoto,;Japan.;Cardiovascular Centre, Nihon University Hospital, Tokyo, Japan.;Department of Cardiovascular Medicine, Faculty of Medicine, Toho University,;Tokyo, Japan.;Department of Cardiology, Kawaguchi Cardiovascular and Respiratory Hospital,;Saitama, Japan. |
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| Pubmed リンク | https://www.ncbi.nlm.nih.gov/pubmed/36173448/ |
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