アブストラクト | Aim: To describe comorbidities among treated nonvalvular atrial fibrillation (NVAF) patients and assess the impact of using different time ('look back' windows) on the prevalence estimates. Patients & methods: We included all adult nonvalvular atrial fibrillation patients newly initiating treatment in the Clinical Practice Research Datalink. Comorbidities included in the Charlson Comorbidity Index were defined using an all available, 3- and 1-year look back window before the start of treatment. Results: The prevalence of comorbidities was high and increased when using longer look back windows; the largest difference was observed for renal disease (+15.6%). Conclusion: Our findings emphasize the importance of using all available data when characterizing chronic conditions and highlights the high comorbidity burden in this population. |
ジャーナル名 | Journal of comparative effectiveness research |
Pubmed追加日 | 2019/7/19 |
投稿者 | Schultze, Anna; Graham, Sophie; Nordstrom, Beth L; Mehmud, Faisal; Ramagopalan, Sreeram V |
組織名 | Data Analytics, Evidera, London, W6 8BJ, UK.;Data Analytics, Evidera, Waltham, MA 02541, USA.;Centre for Observational Research & Data Sciences, Bristol-Myers Squibb,;Uxbridge, UB8 1DH, UK. |
Pubmed リンク | https://www.ncbi.nlm.nih.gov/pubmed/31317772/ |