| アブストラクト | In 1999, the Global Advisory Committee on Vaccine Safety (GACVS) was established by the World Health Organization (WHO) to provide independent scientific advice on issues relating to the safety of vaccines and immunization. Fifteen years onward, we conducted a multi-faceted review to evaluate the impact, reach and challenges facing GACVS, including the role GACVS plays in informing global, regional and WHO member state vaccine policy. The methods included measures of organizational structure, citation impact, themes approached, and a discussion by previous and current members to evaluate past, present and future challenges. Given the increasing range of data sources and the deployment of many new vaccines, the Committee is facing the complex task of identifying the best available evidence for recommendations on vaccine safety. To help meet the increased demand for public transparency in decision making, GACVS-structured methodology for evidence-based decisions is evolving. GACVS also promotes best practices and capacity building for timely and accurate risk assessment; risk communications; outreach to help countries maintain and, if needed, rebuild public trust in vaccines; and advocacy for bridging the major gaps in vaccine safety capacity globally. |
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| 投稿者 | Asturias, Edwin J; Wharton, Melinda; Pless, Robert; MacDonald, Noni E; Chen, Robert T; Andrews, Nicholas; Salisbury, David; Dodoo, Alexander N; Hartigan-Go, Kenneth; Zuber, Patrick L F |
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| 組織名 | Center for Global Health, Colorado School of Public Health, Aurora, CO, USA;;Department of Pediatrics, University of Colorado School of Medicine, Aurora, CO,;USA. Electronic address: edwin.asturias@ucdenver.edu.;National Center for Immunization and Respiratory Diseases, Centers for Disease;Control and Prevention, Atlanta, GA, USA.;Communicable Disease Surveillance, Public Health Agency of Canada, Canada.;Department of Pediatrics, Dalhousie University, Halifax, NS, Canada.;National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, Centers;for Disease Control and Prevention, Atlanta, GA, USA.;Statistics, Modelling and Economics Department, Public Health England, London,;UK.;Centre for Global Health Security, Chatham House, London, UK.;WHO Collaborating Centre for Advocacy and Training in Pharmacovigilance, School;of Medicine and Dentistry, University of Ghana Medical School, Ghana.;Center for Development Management, Asian Institute of Management, Philippines.;Department of Essential Medicines and Health Products, World Health Organization,;Geneva, Switzerland. |
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