| アブストラクト | OBJECTIVES: Adverse reactions to the COVID-19 vaccines have been of interest since their emergency authorization. Cutaneous manifestations of the vaccines are not well studied. We aimed to characterize cutaneous reactions to the Moderna (mRNA-1273) and the Pfizer-BioNTech (BNT162b2) COVID-19 vaccines on a large, national scale. METHODS: The Vaccine Adverse Event Reporting System was filtered for cutaneous and hair and nail reactions to the COVID-19 vaccines. Patient demographics and past medical histories, vaccine manufacturer and dosing, symptom timing, reaction location, and patient outcomes were extracted from each report. RESULTS: As of December 24, 2021, there were 67,273 cutaneous reactions to all COVID-19 vaccines, with most patients receiving the Moderna (mRNA-1273) or Pfizer-BioNTech (BNT162b2) vaccines. The most common reactions overall were injection-site reaction, urticaria, and papular rash, with injection-site reaction more common after the Moderna (mRNA-1273) vaccine, and all other cutaneous reactions more common after the Pfizer-BioNTech (BNT162b2) vaccine. Patients with past histories of psoriasis, urticaria, and local site reactions to a vaccine were more likely to report these same symptoms after the COVID-19 vaccine. CONCLUSION: Patients should be counseled about these potential dermatologic reactions to the COVID-19 vaccines. Most occur within the first few days after vaccination, and are mild and self-limiting. Patients should therefore be encouraged that it is safe to receive the COVID-19 vaccine from a dermatological perspective. |
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| ジャーナル名 | American journal of clinical dermatology |
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| Pubmed追加日 | 2022/8/6 |
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| 投稿者 | Falotico, Julianne M; Desai, Amar D; Shah, Asghar; Ricardo, Jose W; Lipner, Shari R |
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| 組織名 | Renaissance School of Medicine at Stony Brook University, Stony Brook, NY, USA.;Rutgers New Jersey Medical School, Newark, NJ, USA.;Brown University, Providence, RI, USA.;Department of Dermatology, Weill Cornell Medicine, 1305 York Avenue, New York,;NY, 10021, USA.;NY, 10021, USA. shl9032@med.cornell.edu. |
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| Pubmed リンク | https://www.ncbi.nlm.nih.gov/pubmed/35931925/ |
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