| アブストラクト | OBJECTIVES: To evaluate the status of the global standardization of, and prefectural differences in, systematic lupus erythematosus (SLE) treatments in Japan. METHODS: The Japanese National Database of Health Insurance Claims and Specific Health Checkups (NDB Japan) was used. A patient with SLE was defined as having a disease with ICD10 code M321 or M329 between April 2019 and March 2020, for which oral corticosteroids (OCS), immunosuppressive agents or biologic agents were prescribed at least once during a given month. SLE treatments were evaluated by treatment center type and prefecture. RESULTS: In total, 74,277 patients met the definition of SLE. The SLE prevalence was 60 per 100,000 (range: 47 - 102 per 100,000 by prefecture). Nationwide, 79.4% of the patients (range: 52.1% - 93.3% by prefecture) visited a specialized treatment center (STC); 37.4% (range: 26.4% - 51.3% by prefecture) received only OCS, with fewer of these patients visiting a STC than a non-STC (34.8% and 49.7%, p<0.001); and 21.4% (range: 10.7% - 35.0%) received HCQ, with more of these patients visiting a STC than a non-STC (23.0% and 13.5%; p<0.001). CONCLUSIONS: NDB Japan demonstrated delayed global standardization of, and prefectural disparity in, SLE treatments in Japan. |
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| ジャーナル名 | Modern rheumatology |
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| 投稿日 | 2024/8/21 |
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| 投稿者 | Yokogawa, Naoto; Sakai, Ryoko; Matsushita, Masakazu; Shimizu, Masaki; Inoue, Yuzaburo; Inoue, Eisuke; Yamaji, Ken; Mori, Masaaki; Miyamae, Takako |
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| 組織名 | Department of Rheumatic Diseases, Tokyo Metropolitan Tama Medical Center, Tokyo,;Japan.;Department of Public Health and Epidemiology, Meiji Pharmaceutical University,;Tokyo Japan.;Department of Rheumatology, Tokyo Women's Medical University School of Medicine,;Tokyo, Japan.;Department of Internal Medicine and Rheumatology, Juntendo University School of;Medicine, Tokyo, Japan.;Department of Pediatrics and Developmental Biology, Graduate School of Medical;and Dental Sciences, Tokyo Medical and Dental University.;Department of General Medical Science, Graduate School of Medicine, Chiba;University, Chiba, Japan.;Department of Allergy and Rheumatology, Chiba Children's Hospital, Chiba, Japan.;Showa University Research Administration Center, Showa University, Tokyo, Japan.;Department of Lifetime Clinical Immunology, Graduate School of Medical and Dental;Sciences, Tokyo Medical and Dental University, Tokyo, Japan. |
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| Pubmed リンク | https://www.ncbi.nlm.nih.gov/pubmed/39167459/ |
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