| アブストラクト | OBJECTIVES: To investigate the patterns and trends associated with deprescribing of preventive medications in the final 12 months of life in palliative patients living with multiple long-term conditions using the Clinical Practice Research Datalink. PARTICIPANTS: All patients with a medcode/readcode for palliative care assigned to their profile with a medcode/readcode for a cardiometabolic condition. All patients were on therapeutic interventions for their condition/s. PRIMARY AND SECONDARY OUTCOME MEASURES: the trends of medication deprescribing of preventive medications in the final twelve months of life in those known to be end-of-life. RESULTS: Preventive medication deprescribing was only observed in a very small cohort of patients. The findings were consistent across all six medication groups tested. Deprescribing was observed in a range of 2-60 patients with the most deprescribing efforts being associated with antihypertensive medications (n = 177), and antiplatelet medications (n = 70), and antihyperglycaemic medications (n = 10). CONCLUSIONS: Deprescribing practices are not commonplace in patients with a known end-of-life designation with low patient numbers (range 2-60) undergoing the intervention, thus potentially reducing the quality of life in these patients final twelve months of life. CPRD ID: #22_002253, linkage request 2914. |
|---|
| ジャーナル名 | Primary care diabetes |
|---|
| Pubmed追加日 | 2025/3/20 |
|---|
| 投稿者 | Hickman, Elizabeth; Gillies, Clare; Khunti, Kamlesh; Seidu, Samuel |
|---|
| 組織名 | Diabetes Research Centre, Leicester Diabetes Centre, University of Leicester,;Leicester General Hospital, Gwendolen Road, Leicester LE5 4WP, UK. Electronic;address: emh35@leicester.ac.uk.;Leicester General Hospital, Gwendolen Road, Leicester LE5 4WP, UK. |
|---|
| Pubmed リンク | https://www.ncbi.nlm.nih.gov/pubmed/40107899/ |
|---|
