Effect of fluid resuscitation with albumin on mortality in patients with severe burns: A nationwide inpatient data analysis.
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アブストラクト The present study aimed to evaluate the effect of albumin administration on mortality in patients with severe burns. We retrospectively analyzed data from the Diagnosis Procedure Combination Database, a nationwide inpatient database in Japan. We identified patients in the database aged >/= 15 years who were admitted with severe burns (burn index >/=15) from April 2014 to March 2021. We included patients who received albumin within 2 days of admission in the albumin group and those who did not in the control group. The outcome was the 28-day mortality. Eligible patients (n = 2492) were categorized into an albumin group (n = 1128) or a control group (n = 1364). One-to-one propensity score matching generated 530 pairs of patients with and without albumin administration. The 28-day mortality did not differ significantly between the two groups (albumin vs. control, 21.7 % vs. 22.8 %; risk difference, -1.1 %; 95 % confidence interval, -6.1 % to +3.9 %). These results suggest that albumin administration within 2 days of admission in patients with severe burns may not be associated with mortality during the acute phase. ジャーナル名 Burns : journal of the International Society for Burn Injuries 投稿日 2024/9/25 投稿者 Nakamura, Kazuha; Isogai, Toshiaki; Ohbe, Hiroyuki; Nakajima, Mikio; Matsui, Hiroki; Fushimi, Kiyohide; Yasunaga, Hideo 組織名 Department of Clinical Epidemiology and Health Economics, School of Public;Health, The University of Tokyo, Tokyo, Japan; Division of Emergency and;Transport Services, National Center for Child Health and Development, Tokyo,;Japan. Electronic address: kazuha.nakamura.m@gmail.com.;Health, The University of Tokyo, Tokyo, Japan; Department of Cardiology, Tokyo;Metropolitan Tama Medical Center, Tokyo, Japan.;Health, The University of Tokyo, Tokyo, Japan; Department of Emergency and;Critical Care Medicine, Tohoku University Hospital, Miyagi, Japan.;Health, The University of Tokyo, Tokyo, Japan; Emergency and Critical Care;Center, Tokyo Metropolitan Hiroo Hospital, Tokyo, Japan.;Department of Health Services Research, Graduate School of Medicine, The;University of Tokyo, Tokyo, Japan.;Department of Health Policy and Informatics, Graduate School of Medicine, Tokyo;Medical and Dental University, Tokyo, Japan.;Health, The University of Tokyo, Tokyo, Japan. Pubmed リンク https://www.ncbi.nlm.nih.gov/pubmed/39317540/ -
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