| アブストラクト | BACKGROUND: The objective was to report critical respiratory syncytial virus (RSV)-related epidemiological and healthcare resource utilization measures among Japanese children stratified by gestational and chronological age groups. METHODS: The JMDC (formerly the Japan Medical Data Center) was used to retrospectively identify infants with or without RSV infection (beginning between 1 February 2011 and 31 January 2016, with follow-up through 31 December 2017). The incidence of RSV medically attended lower respiratory tract infection (MALRI) was captured by flagging hospitalizations, outpatient, and emergency department/urgent care visits with an RSV diagnosis code during the season. RESULTS: Of 113 529 infants and children identified, 17 022 (15%) had an RSV MALRI (14 590 during the season). The RSV MALRI and hospitalization rates in the first 5 months were 14.3/100 child-years (CY) and 6.0/100 CY, respectively (13.4/100 and 5.8/100 CY for full-term infants and 20/100 and 6.8/100 CY for late preterm infants, respectively). Among those with >/=1 type of MALRI event during the RSV season, >80% of children had it by 24 months of chronological age, although this observation differed by prematurity status. Sixty percent of healthcare resource utilization measures started in the outpatient setting. CONCLUSIONS: This study emphasizes the RSV burden in young children and critically highlights the data needed to make decisions about new preventive strategies. |
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| ジャーナル名 | The Journal of infectious diseases |
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| 投稿日 | 2023/8/26 |
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| 投稿者 | Simoes, Eric A F; Botteman, Marc; Chirikov, Viktor |
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| 組織名 | Department of Pediatrics, University of Colorado School of Medicine, Children's;Hospital Colorado, Aurora, Colorado, USA.;Samshoma Medical Research.;OPEN Health, New York, NY USA. |
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| Pubmed リンク | https://www.ncbi.nlm.nih.gov/pubmed/37625899/ |
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