アブストラクト | Literature, specifically MEDLINE, is among the main sources of information used to detect whether a drug may be responsible for Adverse Drug Reactions cases. The aim of our work is to automate the search of publications that correspond to a given Adverse Drug Reactions case: (i) by defining a general pattern for the queries used to search MEDLINE and (ii) by determining the threshold number of publications capable to confirm or infirm the Adverse Drug Reaction. We applied our algorithm to a set of 620 cases from a French pharmacovigilance database. We obtained a precision of 93%, recall 70%. We determined a threshold of 3 publications to confirm an Adverse Drug Reaction case. |
ジャーナル名 | Studies in health technology and informatics |
投稿日 | 2006/11/17 |
投稿者 | Garcelon, Nicolas; Mougin, Fleur; Bousquet, Cedric; Burgun, Anita |
組織名 | EA 3888, Faculte de Medecine, IFR 140, Universite de Rennes, France.;nicolas.garcelon@univ-rennes1.fr |
Pubmed リンク | https://www.ncbi.nlm.nih.gov/pubmed/17108572/ |