| アブストラクト | Extensive limb swelling (ELS) has been reported after vaccination with a limited number of vaccine types. We sought to describe vaccine types involved in and the clinical characteristics of ELS cases reported to the Vaccine Adverse Event Reporting System (VAERS). A case of ELS was defined as any report of edema extending at least to the elbow or knee of a vaccinated extremity. Four hundred ninety-seven cases were identified, with some describing swelling from the shoulder to the hand or the hip to the foot. Patient age ranged from 0.1 to 91 years. The proportion of reports of ELS associated with a given vaccine, among all VAERS reports received for that vaccine, varied substantially among vaccines. Most reactions began within 1 day after vaccination and involved other signs of inflammation. Postvaccination ELS can involve both the proximal and distal segments of the extremity, affects all age groups, and occurs after vaccination with a broad range of vaccines. |
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| ジャーナル名 | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America |
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| 投稿日 | 2003/7/29 |
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| 投稿者 | Woo, Emily Jane; Burwen, Dale R; Gatumu, Sarah N M; Ball, Robert |
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| 組織名 | Vaccine Safety Branch, Division of Epidemiology, Office of Biostatistics and;Epidemiology, Center for Biologics Evaluation and Research, US Food and Drug;Administration, Rockville, Maryland 20852, USA. wooj@cber.fda.gov |
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| Pubmed リンク | https://www.ncbi.nlm.nih.gov/pubmed/12884159/ |
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