| アブストラクト | BACKGROUND: Aspiration pneumonia (ASP) during hospitalization is associated with poor patient outcomes. We examined the factors associated with ASP onset in older patients in an acute-care hospital in Japan. METHODS: This retrospective cohort study analyzed data from the administrative claims database of patients aged > 65 years hospitalized and discharged from a general acute-care hospital between July 2016 and March 2021. We conducted multivariable logistic regression analyses to identify factors associated with ASP incidence, with independent variables including sex, age (65-74, 75-84, >/= 85 years), place of residence before admission, income, main disease causing admission, dysphagia at admission, Barthel Index at admission, Charlson Comorbidity Index (0, >/= 1), Hospital Frailty Risk Score (0-4, >/= 5), presence of rehabilitation services, surgical treatment, planned hospitalization, enteral nutrition, and total parenteral nutrition. RESULTS: The ASP incidence during hospitalization among the 11,504 included patients (mean age 81.1 years) was 1.6%. ASP incidence was associated with female sex (adjusted odds ratio [aOR]: 0.451, 95% confidence interval [CI]: 0.326-0.625), age >/= 85 years (aOR: 2.901, 95% CI: 1.471-5.718), dysphagia at admission (aOR: 3.810, 95% CI: 1.410-10.293), low activities of daily living level (aOR: 0.971, 95% CI; 0.963-0.979), comorbidities (aOR: 1.839, 95% CI: 1.298-2.605), frailty (aOR: 2.918, 95% CI: 2.089-4.077), unplanned hospitalization (aOR: 3.068, 95% CI: 1.593-5.906), and receiving rehabilitation services during hospitalization (aOR: 0.435, 95% CI: 0.256-0.739). CONCLUSION: This study identified the factors associated with ASP onset in older patients in an acute-care hospital in Japan. These findings may help identify older inpatients who are more likely to develop ASP, supporting the planning of targeted care strategies during hospitalization. |
| 組織名 | Human Care Research Team, Tokyo Metropolitan Institute for Geriatrics and;Gerontology, 35-2 Sakae-cho, Itabashi-ku, Tokyo, 173-0015, Japan.;shohei.yano@gmail.com.;Department of Rehabilitation, Tums Suginami Hospital, 1-40-5 Wada, Suginami-ku,;Tokyo, 166-0012, Japan. shohei.yano@gmail.com. |