| アブストラクト | BACKGROUND: The impact of body mass index (BMI) on hospital mortality in patients with acute heart failure has been well documented in Asian populations. However, the relationship between BMI, hospital-associated disability (HAD), and hospitalization costs in patients with heart failure is poorly understood. This study aimed to explore the impact of BMI on HAD and hospitalization costs for acute heart failure in Japan. METHODS: From April 2012 to March 2020, the Japanese Registry of All Cardiac and Vascular Disease Diagnosis Procedure Combination (JROAD-DPC) database was used to identify patients with acute heart failure. All patients were categorized into five groups according to the World Health Organization Asian BMI criteria. The hospitalization costs and HAD were evaluated. RESULTS: Among the 238,160 eligible patients, 15.7% were underweight, 42.2% were normal, 16.7% were overweight, 19.3% were obese I, and 6.0% were obese II, according to BMI. The prevalence of HAD was 7.43% in the total cohort, and the risk of HAD increased with a lower BMI. Restricted cubic spline analysis showed a U-shaped relationship between BMI and hospitalization costs for all ages. Furthermore, developing HAD was associated with greater costs compared with non-HAD, regardless of BMI category. CONCLUSIONS: We found that the lower the BMI, the higher the incidence of HAD. A U-shaped association was confirmed between BMI and hospitalization costs, indicating that hospitalization costs increased for both lower and higher BMI regardless of age. BMI could be an important and informative risk stratification tool for functional outcomes and economic burdens. |
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| ジャーナル名 | International journal of cardiology |
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| 投稿日 | 2022/8/28 |
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| 投稿者 | Ogawa, Masato; Yoshida, Naofumi; Nakai, Michikazu; Kanaoka, Koshiro; Sumita, Yoko; Kanejima, Yuji; Emoto, Takuo; Saito, Yoshihiro; Yamamoto, Hiroyuki; Sakai, Yoshitada; Hirota, Yushi; Ogawa, Wataru; Iwanaga, Yoshitaka; Miyamoto, Yoshihiro; Yamashita, Tomoya; Izawa, Kazuhiro P; Hirata, Ken-Ichi |
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| 組織名 | Department of Public Health, Graduate School of Health Sciences, Kobe University,;Hyogo, Japan; Division of Rehabilitation Medicine, Kobe University Hospital,;Hyogo, Japan.;Division of Cardiovascular Medicine, Department of Internal Medicine, Kobe;University Graduate School of Medicine, Hyogo, Japan; Division of Endocrinology,;Diabetes and Metabolism, Beth Israel Deaconess Medical Center and Harvard Medical;School, Boston, MA, USA.;Department of Medical and Health Information Management, National Cerebral and;Cardiovascular Center, Osaka, Japan; Department of Biostatistics, National;Cerebral and Cardiovascular Center, Osaka, Japan.;Cardiovascular Center, Osaka, Japan.;University Graduate School of Medicine, Hyogo, Japan.;Division of Rehabilitation Medicine, Kobe University Graduate School of Medicine,;Kobe, Japan.;Division of Diabetes and Endocrinology, Department of Internal Medicine, Kobe;Hyogo, Japan. Electronic address: izawapk@harbor.kobe-u.ac.jp. |
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| Pubmed リンク | https://www.ncbi.nlm.nih.gov/pubmed/36029847/ |
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