| アブストラクト | BACKGROUND: Cardiovascular diseases are the second most common cause of mortality among cancer survivors, after death from cancer. We sought to assess the impact of cancer on the short-term outcomes of acute myocardial infarction (AMI), by analysing data obtained from a large-scale database. METHODS: This study was based on the Diagnosis Procedure Combination database in the Japanese Registry of All Cardiac and Vascular Diseases and the Diagnosis Procedure Combination. We identified patients who were hospitalised for primary AMI between April 2012 and March 2017. Propensity Score (PS) was estimated with logistic regression model, with cancer as the dependent variable and 21 clinically relevant covariates. The main outcome was in-hospital mortality. RESULTS: We split 1 52 208 patients into two groups with or without cancer. Patients with cancer tended to be older (cancer group 73+/-11 years vs non-cancer group 68+/-13 years) and had smaller body mass index (cancer group 22.8+/-3.6 vs non-cancer 23.9+/-4.3). More patients in the non-cancer group had hypertension or dyslipidaemia than their cancer group counterparts. The non-cancer group also had a higher rate of percutaneous coronary intervention (cancer 92.6% vs non-cancer 95.2%). Patients with cancer had a higher 30-day mortality (cancer 6.0% vs non-cancer 5.3%) and total mortality (cancer 8.1% vs non-cancer 6.1%) rate, but this was statistically insignificant after PS matching. CONCLUSION: Cancer did not significantly impact short-term in-hospital mortality rates after hospitalisation for primary AMI. |
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| ジャーナル名 | Open heart |
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| Pubmed追加日 | 2021/11/24 |
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| 投稿者 | Zheng, Robert; Kusunose, Kenya; Okushi, Yuichiro; Okayama, Yoshihiro; Nakai, Michikazu; Sumita, Yoko; Ise, Takayuki; Yamaguchi, Koji; Yagi, Shusuke; Fukuda, Daiju; Yamada, Hirotsugu; Soeki, Takeshi; Wakatsuki, Tetsuzo; Sata, Masataka |
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| 組織名 | Department of Cardiovascular Medicine, Tokushima University Hospital, Tokushima,;Japan.;Japan kusunosek@tokushima-u.ac.jp.;Center for Cerebral and Cardiovascular Disease Information, National Cerebral and;Cardiovascular Center, Osaka, Japan.;Department of Community Medicine for Cardiology, Tokushima University Graduate;School of Biomedical Sciences, Tokushima, Japan. |
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| Pubmed リンク | https://www.ncbi.nlm.nih.gov/pubmed/34810277/ |
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