| アブストラクト | PURPOSE: Hypofractionated radiation therapy (RT) was recommended for several cancer sites to reduce outpatient visits during the COVID-19 pandemic. This study aimed to identify the impact of the pandemic on hypofractionated RT for breast cancer in Japan. METHODS AND MATERIALS: The monthly number of courses for hypofractionated and conventional RTs was counted using sample data sets from the National Database of Health Insurance Claims and Specific Health Checkups of Japan, a nationwide database accumulating insurance claims data comprehensively. Changes in the number of hypofractionated and conventional RTs were estimated using an interrupted time-series analysis. RESULTS: The number of hypofractionated RT courses gradually increased before the pandemic in contrast to that of conventional RT courses, which gradually decreased. However, conventional RT remained outnumbered by hypofractionated RT throughout the observation period. After the outbreak of the pandemic, the use of hypofractionated RT significantly increased in April 2020 (1312 courses; 95% CI, 801-1823) but decreased in October 2020 (-601; 95% CI, -1111 to -92). Subgroup analysis by age and the number of beds in medical institutions revealed similar trends. CONCLUSIONS: Although conventional RT for breast cancer has been gradually replaced by hypofractionated RT, it remains predominant. The use of hypofractionated RT increased briefly early in the COVID-19 pandemic; however, this increase was not sustained, unlike in other countries. Considering the benefits of hypofractionated RT for breast cancer, its use should be encouraged in Japan. |
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| ジャーナル名 | Advances in radiation oncology |
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| 投稿日 | 2024/8/6 |
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| 投稿者 | Fujita, Misuzu; Nagashima, Kengo; Uno, Takashi; Hashimoto, Hideyuki; Suzuki, Kiminori; Kasai, Tokuzo; Yamaguchi, Kazuya; Onouchi, Yoshihiro; Sato, Daisuke; Fujisawa, Takehiko; Hata, Akira |
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| 組織名 | Department of Health Research, Chiba Foundation for Health Promotion and Disease;Prevention, 32-14 Shin-Minato, Mihama-ku, Chiba, Japan.;Department of Public Health, Chiba University Graduate School of Medicine, 1-8-1;Inohana, Chuo-ku, Chiba, Japan.;Biostatistics Unit, Clinical and Translational Research Center, Keio University;Hospital, 35 Shinanomachi, Shinjuku-ku, Tokyo, Japan.;Diagnostic Radiology and Radiation Oncology, Chiba University Graduate School of;Medicine, 1-8-1 Inohana, Chuo-ku, Chiba, Japan.;Hospital and Health Administration, Fujita Health University Graduate School of;Medicine, 1-98 Dengakugakubo, Kutukake-cho, Toyoake, Aichi, Japan. |
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| Pubmed リンク | https://www.ncbi.nlm.nih.gov/pubmed/39104876/ |
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