| アブストラクト | BACKGROUND: Data on the evaluation of the clinical course of coronavirus disease 2019 (COVID-19) and the efficacy of treatments after hospitalization in Japan are limited. OBJECTIVE: This study aimed to construct a database of confirmed COVID-19 cases in Japan and promptly address unresolved research issues. METHODS: This multicenter observational study included patients who had a laboratory-confirmed severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and were discharged from each participating institution between January 1 and September 31, 2020. We called for participating facilities and research proposals until the end of September 2020. The research steering committee members provided advice to co-investigators on refining their research proposals and analyses. After developing the research proposal, we collected clinical information, facility information, and laboratory data from each participating institution. Clinical information was also obtained from the Diagnosis Procedure Combination (DPC) data using a dedicated software called DPC hash application. ANALYSIS: We planned to conduct an analysis based on the research proposal. Overall, 66 institutions from Japan announced their participation, and 102 research proposals were selected for the analyses. Research areas from the proposals included epidemiology, pathophysiology, therapeutic agents, ventilator settings, cost-benefit analyses, and prognosis prediction for COVID-19. CONTRIBUTION AND SIGNIFICANCE TO THE FIELD: We have established an efficient data collection system and clinical research team for COVID-19 infection studies. The results of this study may be utilized in future response strategies for COVID-19. |
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| ジャーナル名 | Annals of clinical epidemiology |
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| 投稿日 | 2022/3/11 |
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| 投稿者 | Tagami, Takashi; Yamakawa, Kazuma; Endo, Akira; Hayakawa, Mineji; Ogura, Takayuki; Hirayama, Atsushi; Yasunaga, Hideo |
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| 組織名 | Department of Emergency and Critical Care Medicine, Nippon Medical School;Musashikosugi Hospital.;Department of Clinical Epidemiology and Health Economics, School of Public;Health, The University of Tokyo.;Department of Emergency Medicine, Osaka Medical and Pharmaceutical University.;Trauma and Acute Critical Care Center, Tokyo Medical and Dental University;Hospital.;Department of Emergency Medicine, Hokkaido University Hospital.;Department of Emergency Medicine and Critical Care Medicine, Tochigi Prefectural;Emergency and Critical Care Centre, Imperial Foundation Saiseikai Utsunomiya;Public Health, Department of Social Medicine, Graduate School of Medicine, Osaka;University. |
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| Pubmed リンク | https://www.ncbi.nlm.nih.gov/pubmed/38504944/ |
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