| アブストラクト | Tumor necrosis factor alpha inhibitors (anti-TNFalpha) drugs may give rise to serious adverse effects resulting from immunosupresion [1]. Kaposi sarcoma (KS) is a neoplasm that affects the vascular endothelium; infection with type-8 human herpesvirus (HHV-8) and immunosuppression are both necessary etiological factors for this condition to occur [2]. To address the potential causal relationship between KS and anti-TNFalpha drugs, we conducted a case-non case study in the WHO pharmacovigilance database, VigiBase. |
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| ジャーナル名 | Journal of the European Academy of Dermatology and Venereology : JEADV |
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| 投稿日 | 2019/11/17 |
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| 投稿者 | Sainz-Gil, M; Rodriguez-Jimenez, P; Cardaba, M E; Martin Arias, L H |
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| 組織名 | Centro de Estudios sobre la Seguridad de los Medicamentos (CESME), Facultad de;Medicina, Universidad de Valladolid, Spain.;Centro de Farmacovigilancia de Castilla y Leon. Facultad de Medicina, Universidad;de Valladolid, Spain.;Servicio de Dermatologia, Hospital Universitario de La Princesa, Madrid, Spain.;Servicio de Farmacia, Hospital del Tajo, Aranjuez (Madrid), Spain. |
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| Pubmed リンク | https://www.ncbi.nlm.nih.gov/pubmed/31733080/ |
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