| アブストラクト | PURPOSE: Long-term medical needs after definitive surgery for esophageal atresia (EA) are incompletely understood. The real-world patterns of home medical care and medication use after hospital discharge remain underexplored. METHODS: Using the Japanese national inpatient Diagnosis Procedure Combination database, we identified infants who underwent definitive surgery for EA between July 2010 and March 2023. We described patients' background characteristics, perioperative information, long-term home medical care (home tracheostomy care, home mechanical ventilation, home oxygen therapy, and home enteral nutrition), and medication use (antacids, prokinetic agents, and anti-asthmatics) at 1, 3, 5, and 7 years post-definitive surgery. Subgroup analysis based on congenital heart disease (CHD) was conducted. RESULTS: Overall, 806 patients met the eligibility criteria. Home enteral nutrition was the most frequently performed home medical care (22.0% of patients at 1 year post-surgery), whose proportion decreased gradually over time. Antacid and prokinetic agent use also declined over time. Subgroup analysis revealed that patients with CHD required home oxygen therapy and home enteral nutrition more frequently than those without CHD. CONCLUSIONS: A substantial proportion of patients required home longitudinal nutritional and respiratory support post-definitive surgery for EA. Our findings provide important information for long-term healthcare needs of patients receiving definitive surgery for EA. LEVEL OF EVIDENCE: III (retrospective comparative study). |
|---|
| 投稿者 | Yanagida, Yoshitsugu; Aso, Shotaro; Fujiogi, Michimasa; Kirino, Kosuke; Ishimaru, Tetsuya; Santo, Kenji; Uehara, Shuichiro; Taguchi, Tomoaki; Yoshimura, Kensuke; Yasunaga, Hideo; Fujishiro, Jun |
|---|
| 組織名 | Department of Pediatric Surgery, Graduate School of Medicine, The University of;Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan.;Department of Clinical Epidemiology and Health Economics, School of Public;Health, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan.;Department of Health Services Research, Graduate School of Medicine, The;University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan.;Department of Data Science, Clinical Research Center, National Center for Child;Health and Development, 2-10-1 Okura, Setagaya-ku, Tokyo, 157-8535, Japan.;Division of Surgery, Department of Surgical Specialties, National Center for;Child Health and Development, 2-10-1 Okura, Setagaya-ku, Tokyo, 157-8535, Japan.;Department of Pediatric Surgery, Nihon University School of Medicine, 1-1-5;Sendagi, Bunkyo-ku, Tokyo, 113-8603, Japan.;Fukuoka College of Health Sciences, 2-15-1 Tamura, Sawara-ku, Fukuoka, 814- 0139,;Japan.;Center for Next Generation of Community Health, Chiba University Hospital, 1-8-1,;Inohana, Chuo-ku, Chiba-shi, Chiba, 260-8677, Japan.;FUJISHIROJ-PSU@h.u-tokyo.ac.jp. |
|---|
