| アブストラクト | AIM: Although major complication rates following percutaneous liver biopsy (PLB) have been reported to be higher in children than in adults, scarce data are available regarding pediatric patients stratified by native and transplanted liver. We aimed to assess the factors associated with major complications after percutaneous biopsy of native or transplanted liver using a nationwide inpatient database. METHODS: Using the Japanese Diagnosis Procedure Combination database, we retrospectively identified pediatric patients who underwent PLB between 2010 and 2018. We described major complication rates and analyzed factors associated with major complications following PLB, stratified by native and transplanted liver. RESULTS: We identified 3584 pediatric PLBs among 1732 patients from 239 hospitals throughout Japan during the study period, including 1310 in the native liver and 2274 in the transplanted liver. Major complications following PLB were observed in 0.5% (n = 18) of the total cases; PLB in the transplanted liver had major complications less frequently than those in the native liver (0.2% vs. 1.0%, p = 0.002). The occurrence of major complications was associated with younger age, liver cancers, unscheduled admission, anemia or coagulation disorders in cases with native liver, while it was associated with younger age alone in cases with transplanted liver. CONCLUSIONS: The present study, using a nationwide database, found that major complications occurred more frequently in pediatric cases with native liver and identified several factors associated with its major complications. |
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| 投稿者 | Kurakawa, Kayo Ikeda; Okada, Akira; Bessho, Kazuhiko; Jo, Taisuke; Ono, Sachiko; Michihata, Nobuaki; Kumazawa, Ryosuke; Matsui, Hiroki; Fushimi, Kiyohide; Yamaguchi, Satoko; Yamauchi, Toshimasa; Nangaku, Masaomi; Kadowaki, Takashi; Yasunaga, Hideo |
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| 組織名 | Department of Prevention of Diabetes and Lifestyle-Related Diseases, Graduate;School of Medicine, The University of Tokyo, Tokyo, Japan.;Department of Pediatrics, National Rehabilitation Center for Persons With;Disabilities, Saitama, Japan.;Department of Pediatrics, Graduate School of Medicine, Osaka University, Osaka,;Japan.;Department of Health Services Research, Graduate School of Medicine, The;University of Tokyo, Tokyo, Japan.;Department of Eat-Loss Medicine, Graduate School of Medicine, The University of;Tokyo, Tokyo, Japan.;Department of Clinical Epidemiology and Health Economics, School of Public;Health, The University of Tokyo, Tokyo, Japan.;Department of Health Policy and Informatics, Tokyo Medical and Dental University;Graduate School of Medicine, Tokyo, Japan.;Department of Diabetes and Metabolism, Graduate School of Medicine, The;Department of Nephrology and Endocrinology, Graduate School of Medicine, The;t-kadowaki@toranomon.kkr.or.jp.;Toranomon Hospital, 2-2-2, Toranomon, Minato-ku, Tokyo, 105-8470, Japan. |
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