| アブストラクト | OBJECTIVE: Research shows that people with a history of mental health conditions were at increased risk of COVID-19 infection, hospitalisation, and mortality. However, the relationship between mental health conditions and COVID-19 vaccine outcomes such as vaccine intention, uptake and vaccine breakthrough is not yet well-understood. METHODS: We conducted a systematic search on the topics of COVID-19 vaccine intentions, vaccine uptake, and vaccine breakthrough, in relation to mental health conditions (e.g., depression, schizophrenia), in four databases: PubMed, MEDLINE, SCOPUS, and PsychINFO, and the publication lists of Clinical Practice Research Datalink (CPRD), The Health Improvement Network (THIN), OpenSAFELY, and QResearch. Inclusion criteria focussed on studies reporting any of the aforementioned COVID-19 vaccine outcomes among people with mental health conditions. RESULTS: Of 251 publications initially identified, 32 met our inclusion criteria. Overall, the evidence is inconclusive regarding the levels of intention to accept COVID-19 vaccines among people with mental health conditions. People with mental health conditions were more likely to have lower uptake of COVID-19 vaccines, compared to people without. Common barriers to COVID-19 vaccine uptake included concerns about the safety, effectiveness, and side effects of the vaccines. Limited evidence also suggests that vaccine breakthrough may be a particular risk for those with substance use disorder. CONCLUSIONS: Evidence for the association between COVID-19 vaccine intentions and mental health conditions is mixed. Vaccine uptake might be lower in people with mental health conditions compared to people without, yielding interventions to encourage vaccine uptake in this population. Our understanding of COVID-19 vaccine breakthrough in this population also needs enhancing. |
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| ジャーナル名 | Journal of psychosomatic research |
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| 投稿日 | 2024/6/13 |
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| 投稿者 | Jia, Ru; Coupland, Carol; Vinogradova, Yana; Qureshi, Nadeem; Turner, Emma; Vedhara, Kavita |
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| 組織名 | Nuffield Department of Primary Care Health Sciences, Medical Science Division,;University of Oxford, Radcliffe Observatory Quarter, Oxford, OX2 6GG, UK.;University of Oxford, Radcliffe Observatory Quarter, Oxford, OX2 6GG, UK; Centre;for Academic Primary Care, Lifespan and Population Health, School of Medicine,;University of Nottingham, University Park, Nottingham NG7 2RD, UK.;Centre for Academic Primary Care, Lifespan and Population Health, School of;Medicine, University of Nottingham, University Park, Nottingham NG7 2RD, UK.;Bristol Medical School, University of Bristol, Bristol BS8 1QU, UK.;School of Psychology, Cardiff University, Tower Building, Cardiff CF10 3AT, UK.;Electronic address: VedharaK@cardiff.ac.uk. |
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| Pubmed リンク | https://www.ncbi.nlm.nih.gov/pubmed/38870550/ |
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