| アブストラクト | BACKGROUND: Previous observational studies have reported a higher risk of stroke in migraine patients. Objective.- We aimed to estimate the risk of stroke, transient ischemic attack (TIA), or death in migraineurs in the UK. METHOD: We conducted a population-based follow-up study within the General Practice Research Database from 1994 to 2001. RESULTS: The relative risk (RR) of stroke in migraineurs compared with non-migraineurs was 2.2 (95% confidence interval [CI] 1.7-2.9). It was highest for patients with a migraine diagnosis recorded within 30 days prior to a stroke (odds ratio 11.1, 95% CI 5.69-21.5). The RR of TIA in migraineurs compared with non-migraineurs was 2.4 (95% CI 1.8-3.3), the mortality of migraineurs was slightly decreased. CONCLUSION: In our study, the RR of developing a stroke or a TIA was doubled in migraineurs as compared with non-migraineurs, while that for death was close to unity. |
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| ジャーナル名 | Headache |
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| Pubmed追加日 | 2007/12/7 |
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| 投稿者 | Becker, Claudia; Brobert, Gunnar P; Almqvist, Per M; Johansson, Saga; Jick, Susan S; Meier, Christoph R |
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| 組織名 | Basel Pharmacoepidemiology Unit, Division of Clinical Pharmacology and;Toxicology, University Hospital Basel, Switzerland. |
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| Pubmed リンク | https://www.ncbi.nlm.nih.gov/pubmed/18052947/ |
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