| アブストラクト | BACKGROUND: The COVID-19 pandemic posed substantial challenges to healthcare systems. Understanding the responses of pediatric health services is crucial for future pandemic planning and preparedness, yet such data remains limited. METHODS: In this retrospective cohort study, we analyzed data from administrative databases developed by Japan Medical Data Center and DeSC Healthcare Inc. The dataset comprised records of 2,612,511 children, totaling 60,224,888 person-months, from January 2020 to May 2022. Multivariate generalized estimation equations were used to examine the incidence rates of COVID-19 and associated health resource use. RESULTS: Our analysis revealed that the incidence rates of COVID-19 gradually increased from Wave I (2.2 cases per 100,000 person-months) to Wave V (177.8cases per 100,000 person-months), with a notable elevation during Wave VI (2367.7 cases per 100,000 person-months). While nucleic acid amplification tests were primarily used during Waves I-V, the use of rapid antigen tests markedly increased in Wave VI. The hospitalization rates increased gradually from 0.2 in Wave I to 10.2 events per 100,000 person-months in Wave VI, and the case-hospitalization risk decreased from 14.9% in Wave II to 0.7% in Wave VI. Additionally, we observed decreasing trends in the use of antibiotics (Wave I, 31.8%; Wave VI, 9.0%), whereas antipyretic use rose from Wave I (56.1%) to Wave VI (86.6%). CONCLUSIONS: Our study highlighted essential changes in the nationwide pediatric healthcare system's response to the COVID-19 pandemic. These findings provide valuable insights into the future pandemic planning and preparedness. |
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| ジャーナル名 | Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy |
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| 投稿日 | 2024/4/9 |
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| 投稿者 | Okubo, Yusuke; Nakabayashi, Yosuke; Ito, Kenta; Uda, Kazuhiro; Miyairi, Isao |
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| 組織名 | Department of Social Medicine, National Center for Child Health and Development,;Tokyo, Japan. Electronic address: okubo-y@ncchd.go.jp.;Department of Emergency Medicine, Maebashi Red Cross Hospital, Gunma, Japan.;Department of General Pediatrics, Aichi Children's Health and Medicine Hospital,;Obu, Japan.;Department of Pediatrics, Okayama University Graduate School of Medicine,;Dentistry, and Pharmaceutical Science, Okayama, Japan.;Department of Pediatrics, Hamamatsu University School of Medicine, Shizuoka,;Japan; Department of Microbiology, Immunology, and Biochemistry, University of;Tennessee Health Science Center, Tennessee, USA. |
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| Pubmed リンク | https://www.ncbi.nlm.nih.gov/pubmed/38588796/ |
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