| アブストラクト | Since the 1990s, polymyalgia rheumatica (PMR) has been reported as a possible adverse event following immunization (AEFI). The aim of this narrative review is to provide an overview of PMR (and PMR-like syndromes) following the most common types of COVID-19 vaccines, namely mRNA (tozinameran and mRNA-1273) and adenovirus-vectored (ChAdOx1-S) vaccines. To date, published literature reports few cases of PMR as vaccine-linked AEFI. Yet Vigibase, the WHO pharmacovigilance database, reports a few hundred cases. Based on these data, we address the question whether PMR/PMR-like syndromes following COVID-19 vaccines can be a true adverse or a coincidental event, and discuss its possible pathogenetic mechanisms. |
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| ジャーナル名 | Reumatologia |
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| 投稿日 | 2022/7/6 |
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| 投稿者 | Manzo, Ciro; Castagna, Alberto; Isetta, Marco |
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| 組織名 | Azienda Sanitaria Locale Napoli 3 sud, Internal and Geriatric Medicine;Department, Rheumatologic Outpatient Clinic, Sant'Agnello, Naples, Italy.;Azienda Sanitaria Provinciale Catanzaro, Primary Care Department, Soverato,;Catanzaro, Italy.;Central and North West London NHS Trust, England. |
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| Pubmed リンク | https://www.ncbi.nlm.nih.gov/pubmed/35782034/ |
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